(19)
(11) EP 1 653 996 A2

(12)

(88) Date of publication A3:
28.07.2005

(43) Date of publication:
10.05.2006 Bulletin 2006/19

(21) Application number: 04739027.3

(22) Date of filing: 09.08.2004
(51) International Patent Classification (IPC): 
A61K 38/36(1995.01)
(86) International application number:
PCT/DK2004/000530
(87) International publication number:
WO 2005/014035 (17.02.2005 Gazette 2005/07)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

(30) Priority: 08.08.2003 DK 200301145
12.08.2003 US 494447 P
05.11.2003 DK 200301646
12.11.2003 US 519212 P

(71) Applicant: Novo Nordisk Health Care AG
8050 Zürich (CH)

(72) Inventors:
  • BEHRENS, Carsten
    DK-2200 Copenhagen N (DK)
  • GARIBAY, Patrick, William
    DK-2840 Holte (DK)
  • ZUNDEL, Magali
    DK-2860 Söborg (DK)
  • KLAUSEN, Niels, Kristian
    DK-2820 Gentofte (DK)
  • BJÖRN, Sören, E.
    DK-2880 Lyngby (DK)

(74) Representative: Nilsson, Karin Norvin 
Novo Nordisk A/S, Corporate Patents, Novo Allé
2880 Bagsvaerd
2880 Bagsvaerd (DK)

   


(54) USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST