(19)

(11)

EP 1 660 451 A2

(12)

(88) Date of publication A3: 02.06.2005 (43) Date of publication: 31.05.2006 Bulletin 2006/22 (21) Application number: 04775682.0 (22) Date of filing: 01.09.2004

(51) International Patent Classification (IPC):  C07D 209/88(1985.01) (86) International application number: PCT/SI2004/000029 (87) International publication number: WO 2005/021504 (10.03.2005 Gazette 2005/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 02.09.2003 SI 200300218 (71) Applicant: KRKA, tovarna zdravil, d.d., Novo mesto 8501 Novo mesto (SI)	(72) Inventors: ZUPET, Rok 1211 Ljubljana (SI) GRCMAN, Marija 8212 Velika Loka (SI) SMRKOLJ, Matej 1411 Izlake (SI) (74) Representative: Becker Kurig Straus  Patentanwälte Bavariastrasse 7 D-80336 München D-80336 München (DE)