(19)
(11) EP 1 660 454 A1

(12)

(43) Date of publication:
31.05.2006 Bulletin 2006/22

(21) Application number: 04743288.5

(22) Date of filing: 07.07.2004
(51) International Patent Classification (IPC): 
C07D 217/04(1985.01)
C07D 403/06(1990.01)
A61K 31/472(2000.01)
A61K 31/55(1985.01)
C07D 209/44(1985.01)
C07D 223/16(1985.01)
A61K 31/4035(2000.01)
A61P 25/04(2000.01)
(86) International application number:
PCT/GB2004/002945
(87) International publication number:
WO 2005/005392 (20.01.2005 Gazette 2005/03)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

(30) Priority: 07.07.2003 GB 0315872
21.07.2003 US 488442 P

(71) Applicant: Vernalis (R&D) Limited
Winnersh Berkshire RG14 5UA (GB)

(72) Inventors:
  • Hamlyn, Richard, John, Ionix Pharmaceuticals Ltd.
    Milton Road, Cambridge CB4 0PA (GB)
  • Huckstep, Michael Richard, Ionix Pharm. Ltd
    Milton Road, Cambridge CB4 0PA (GB)
  • Lynch, Rosemary, Ionix Pharmaceuticals Ltd
    Milton Road, Cambridge CB4 0PA (GB)
  • Stokes, Stephen, Ionix Pharmaceuticals Ltd
    Milton Road, Cambridge CB4 0PA (GB)
  • Tickle, David Christopher, Ionix Pharm. Ltd
    Milton Road, Cambridge CB4 0PA (GB)
  • Patient, Lee, Ionix Pharmaceuticals Ltd
    Milton Road, Cambridge CB4 0PA (GB)

(74) Representative: Baker-Munton, Nicola Jane 
Stratagem IPM Fosters Wing, Anstey Hall
Maris Lane Trumpington Cambridge, CB2 2LG
Maris Lane Trumpington Cambridge, CB2 2LG (GB)

   


(54) AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS