Technical field
[0001] The present invention relates to detergent compositions, particularly laundry detergent
compositions and in particular to detergents comprising lipolytic or lipase enzymes.
Background of the Invention and Prior Art
[0002] Lipase enzymes have been used in detergents since the late 1980s for removal of fatty
soils. It is known that lipase enzymes impact perfumes of detergent compositions containing
them. The selection of perfumes for use in detergent compositions comprising lipase
enzymes is documented in EP-A-430315, where it is described that in order to combat
malodours resulting from the use of lipase enzymes, perfumes should be used that comprise
at least 25% by weight of defined perfume materials and less than 50% by weight of
esters derived from fatty acids with 1-7 carbon atoms.
[0003] Until relatively recently, the main commercially available lipase enzymes worked
particularly effectively at the lower moisture levels of the drying phase of the wash
process. However, more recently, higher efficiency lipases have been developed that
also work effectively during the wash phase of the cleaning process. Examples of such
enzymes are as described in WO00/60063 and Research Disclsoure IP6553D. This makes
it even more difficult for the detergent formulator to produce consumer acceptable
perfumes in a climate where consumers' expectation is increasingly for pleasant perfumes
at all stages of the washing process. One particular area where the impact of lipase
on the perfume in the detergent composition can be most noticeable to consumers is
after storage and as a result, during the washing process. This can be a particular
problem for detergents for use in hand-washing processes. The present inventors have
found that the problems described above can be alleviated even for detergent formulations
comprising the new high efficiency lipase enzymes. Furthermore, the present inventors
have found specific preferred perfumes for use in such detergent formulations.
Definition of the Invention
[0004] In accordance with the present invention there is provided a detergent composition
comprising:
- 1. a lipase which is a polypeptide having an amino acid sequence which: (a) has at
least 90% identity with the wild-type lipase derived from Humicola lanuginosa strain DSM 4109; (b) compared to said wild-type lipase, comprises a substitution
of an electrically neutral or negatively charged amino acid at the surface of the
three-dimensional structure within lSAngstroms of E1 or Q249 with a positively charged
amino acid; and (c) comprises a peptide addition at the C-tenninal; and/or (d) comprises
a peptide addition at the N-terminal and/or (e) meets the following limitations: i)
comprises a negative amino acid in position E210 of said wild-type lipase; ii) comprises
a negatively charged amino acid in the region corresponding to positions 90-101 of
said wild-type lipase; and iii) comprises a neutral or negative amino acid at a position
corresponding to N94 of said wild-type lipase and/or has a negative or neutral net
electric charge in the region corresponding to positions 90-101 of said wild-type
lipase; and
- 2. an encapsulated perfume particle comprising (a) an at least partially water-soluble
solid matrix comprising one or more water-soluble hydroxylic compounds, preferably
starch; and (b) a perfume oil encapsulated by the solid matrix.
[0005] The lipase enzyme may be a polypeptide as defined above, meeting criteria (a) and
(b) and (c) and/or (e).
[0006] In a further embodiment of the invention, the encapsulated perfume oil comprises
at least 1 % by weight or at least 5wt% or even at least 10% by weight, or even at
least 20%, 30, 40, 50, 60, 70, 80 or 90 % by weight of at least one perfume ingredient
having a boiling point at 36KNm
-2 (760mmHg) of 260°C or lower and a calculated log
10 of its octanol/water coefficient P (ClogP), of at least 3.0. In a further embodiment,
the encapsulated perfume oil comprises at least one ester derived from fatty acids
with 1-7 carbon atoms, generally at least 1 % by weight or at least 5wt% or even at
least 10% by weight, or even at least 20%, 30, 40, 50, 60, 70, 80 or 90 wt% ester
by weight based on the weight of the total perfume oil in the encapsulated perfume
particle. The inventors have found that two particular perfume esters are especially
sensitive to the presence of lipase enzymes so that the invention is particularly
beneficial where the encapsulated perfume oil comprises benzyl acetate and/or phenylethyl
acetate,
In a further embodiment of the invention, there is provided a detergent composition
comprising a perfume composition, said perfume composition comprising the perfume
oil in the encapsulated perfume particle and any optional additional pefume oil, said
perfume composition comprising at least 10% by weight, or at least 20, 30, 40, 50,
60, 70, 80 or even 90 wt% of one or more perfume components having a molecular weight
of greater than 0 but less than or equal to 350 daltons, at least 80% of said one
or more perfume components having a cLogP of at least 2.4, said perfume composition
comprising at least 5% of said one or more perfume components having a cLogP of at
least 2.4.
Detailed Description of the Invention
[0007] All percentages and ratios herein are calculated by weight unless otherwise indicated.
Percentages and ratios are calculated based on the total composition unless otherwise
indicated. The nomenclature used herein describing the enzymes, for example relating
to amino acid modifications, amino acid groupings and amino acid identity is as in
WO00/60063.
[0008] The lipase enzymes suitable for use in the present invention may be selected from
the group consisting of enzymes capable of hydrolyzing ester bonds, classified by
EC number 3.1, preferably enzymes that hydrolyze carboxylic ester bonds, classified
by EC number 3.1.1 Within this class, particularly preferred are lipases classified
by EC number 3.1.1.3 and most preferred are those with first wash performance such
as are described in WO00/60063, WO99/42566 WO02/062973, WO97/04078, WO97/04079 and
US5869438.
[0009] The preferred lipase enzymes are described in WO00/60063. The preferred lipases suitable
for use in the present invention as described in WO00/60063 are described with reference
to a lipase that is the wild-type lipase derived from
Humicola Lanuginosa strain DSM 4109 (reference lipase). The reference lipase is also referred to as Lipolase
(registered trade name of Novozymes). It is described in EP258068 and EP305216 and
has the amino acid sequence shown in positionsl-269 of SEQ ID No 2 of US5869438.
[0010] The most preferred first wash lipase for use in the present invention is available
under the tradename LIPEX (registered tradename of Novozymes), a variant of the
Humicola lanuginasa (Thermomyces lanugina.sus) lipase (Lipolase registered tradename of Novozymes) with the mutations T231R and
N233R.
[0011] The lipase enzyme incorporated into the detergent compositions of the present invention
is generally present in an amount of 10 to 20000 LU/g of the detergent composition,
or even 100 to 10000 LU/g. The LU unit for lipase activity is defined in WO99/42566.
The lipase dosage in the wash solution is typically from 0.02 to 2 mg/l enzyme, more
typically from 0.1 to 2mg/l as enzyme protein.
[0012] The lipase enzyme may be incorporated into the detergent composition in any convenient
form, generally in the form of a non-dusting granulate, a stabilised liquid or a coated
enzyme particle. Alternatively a slurry may be suitable.
[0013] The at least partially water soluble hydroxylic compounds useful herein are preferably
selected from carbohydrates, which can be any or mixture of: i) simple sugars (or
mono-saccharides); ii) oligosaccharides (defined as carbohydrate chains consisting
of 2-10 monosaccharide molecules); iii) polysaccharides (defined as carbohydrate chains
consisting of at least 11, or more usually at least 35 monosaccharide molecules);
and iv) starches.
[0014] Both linear and branched carbohydrate chains may be used. In addition chemically
modified starches and poly-/oligo-saccharides may be used. Typical modifications include
the addition of hydrophobic moieties of the form of alkyl, aryl, etc. identical to
those found in surfactants to impart some surface activity to these compounds.
[0015] Other examples of suitable encapsulating materials include all natural or synthetic
gums such as alginate esters, carrageenin, agar-agar, pectic acid, and natural gums
such as gum arabic, gum tragacanth and gum karaya, chitin and chitosan, cellulose
and cellulose derivatives including i) cellulose acetate and cellulose acetate phthalate
(CAP); ii) hydroxypropyl methyl cellulose (HPMC); iii)carboxymethylcellulose (CMC);
iv) all enteric/aquateric coatings and mixtures thereof.
[0016] Particularly preferred encapsulating matrix materials comprise starches. Suitable
examples can be made from, raw starch, pregelatinized starch, modified starch derived
from tubers, legumes, cereal and grains, for example corn starch, wheat starch, rice
starch, waxy corn starch, oat starch, cassava starch, waxy barley, waxy rice starch,
sweet rice starch, amioca, potato starch, tapioca starch, oat starch, cassava starch,
and mixtures thereof.
[0017] Modified starches suitable for use as the encapsulating matrix in the present invention
include, hydrolyzed starch, acid thinned starch, starch esters of long chain hydrocarbons,
starch acetates, starch octenyl succinate, and mixtures thereof.
[0018] The term "hydrolyzed starch" refers to oligosaccharide-type materials that are typically
obtained by acid and/or enzymatic hydrolysis of starches, preferably corn starch.
Suitable hydrolyzed starches for inclusion in the present invention include maltodextrins
and corn syrup solids. The hydrolyzed starches for inclusion with the mixture of starch
esters have a Dextrose Equivalent (DE) values of from about 10 to about 36 DE. The
DE value is a measure of the reducing equivalence of the hydrolyzed starch referenced
to dextrose and expressed as a percent (on a dry basis). The higher the DE value,
the more reducing sugars present. A method for determining DE values can be found
in Standard Analytical Methods of the Member Companies of Corn Industries Research
Foundation, 6th ed. Corn Refineries Association, Inc, Washington, DC 1980, D-52.
[0019] Starch esters having a degree of substitution in the range of from about 0.01% to
about 10.0% may be used to encapsulate the perfume oils of the present invention.
The hydrocarbon part of the modifying ester should be from a C
5 to C
16 carbon chain. Preferably, octenylsuccinate (OSAN) substituted waxy corn starches
of various types such as 1) waxy starch: acid thinned and OSAN substituted, 2) blend
of corn syrup solids: waxy starch, OSAN substituted, and dextrinized, 3) waxy starch:
OSAN substituted and dextrinized, 4) blend of corn syrup solids or maltodextrins with
waxy starch: acid thinned OSAN substituted, and then cooked and spray dried, 5) waxy
starch: acid thinned and OSAN substituted then cooked and spray dried, and 6) the
high and low viscosities of the above modifications (based on the level of acid treatment)
can also be used in the present invention.
[0020] Modified starches having emulsifying and emulsion stabilizing capacity such as starch
octenyl succinates have the ability to entrap the perfume oil droplets in the emulsion
due to the hydrophobic character of the starch modifying agent. The perfume oils remain
trapped in the modified starch until dissolved in the wash solution, due to thermodynamic
factors i.e., hydrophobic interactions and stabilization of the emulsion because of
steric hindrance. The perfume may be adsorbed or adsorbed onto a carrier prior to
encapsulation. Suitable examples of carriers are as described in WO.97/11151 or may
be polymeric materials. Zeolite is a particularly preferred carrier, for example as
described in more detail in WO97/11151.
[0021] Other known methods of manufacturing the starch encapsulates of the present invention,
include but are not limited to, fluid bed agglomeration, extrusion, cooling/crystallization
methods and the use of phase transfer catalysts to promote interfacial polyrnerization.
[0022] Other suitable matrix materials and process details are disclosed in, e.g., U.S.
Pat. No. 3,971,852, Brenner et al., issued July 27, 1976.
Perfume Oils
[0023] As used herein, the expression "perfume oil" is intended to refer to perfume raw
materials or ingredients, or combinations thereof. Whilst these are generally immiscible
with water under standard conditions of temperature and pressure, a small number may
be miscible with water. The perfume oil may comprise one perfume ingredient or mixtures
of more than one perfume ingredient. In addition to the perfume oil present in the
detergent compositions of the invention via the encapsulated perfume particle, additional
perfume oils may be present in the detergent via other delivery systems as discussed
below. The overall sum of perfume ingredients present in the encapsulated perfume
oil and any optional additional perfume oils provides the perfume composition of the
detergent composition.
[0024] The inventors have found that often lipase enzymes and particularly the high efficiency
lipase enzymes essential for the present invention, are problematic for perfume stability
on storage and this means that the perfume fragrance detected by the consumer is not
only reduced compared with the amount of perfume added into the detergent formulation
but may also be adversely affected so that it is not the perfume selected by the perfumer.
This problem is particularly noticeable by the consumer during the washing process
and the inventors have found that not only do the encapsulated perfumes have a degree
of protection on storage, but also surprisingly, the encapsulated perfumes appear
to be chaperoned to the surface of the wash water by the encapsulate, providing maximum
efficacy for the perfume raw materials used. The use of the encapsulated perfumes
in combination with the specified lipases also provides a degree of protection from
these particularly lipase-sensitive perfume raw materials.
[0025] Preferably the perfume oil present in the encapsulated perfume particle comprises
one or more perfume ingredient characterized by its boiling point (B.P.) and its octanol/water
partition coefficient (P). The octanol/water partition coefficient of a perfume ingredient
is the ratio between its equilibrium concentrations in octanol and in water. The preferred
perfume ingredients of this invention have a B.P., determined at the normal, standard
pressure of about 760 mm Hg, of about 260°C or lower, preferably less than about 255°C;
and more preferably less than about 250°C, and an octanol/water partition coefficent
P of about 1,000 or higher. Since the partition coefficients of the preferred perfume
ingredients of this invention have high values, they are more conveniently given in
the form of their logarithm to the base 10, logP. Thus the preferred perfume ingredients
of this invention have logP of at least 3, preferably more than 3.1, and even more
preferably more than 3.2.
[0026] The boiling points of many perfume ingredients are given in, e.g., "Perfume and Flavor
Chemicals (Aroma Chemicals)," Steffen Arctander, published by the author, 1969, incorporated
herein by reference.
[0027] The logP of many perfume ingredients has been reported; for example, the Pomona92
database, available from Daylight Chemical Information Systems, Inc. (Daylight CIS),
Irvine, California, contains many, along with citations to the original literature.
However, the logP values are most conveniently calculated by the "CLOGP" program,
also available from Daylight CIS. This program also lists experimental logP values
when they are available in the Pomona92 database. The "calculated logP" (ClogP) is
determined by the fragment approach of Hansch and Leo (cf., A. Leo, in Comprehensive
Medicinal Chemistry, Vol. 4, C. Hansch, P. G. Sammens, J. B. Taylor and C. A. Ramsden,
Eds., p. 295, Pergamon Press, 1990, incorporated herein by reference). The fragment
approach is based on the chemical structure of each perfume ingredient, and takes
into account the numbers and types of atoms, the atom connectivity, and chemical bonding.
The ClogP values, which are the most reliable and widely used estimates for this physicochemical
property, are preferably used instead of the experimental logP values in the selection
of perfume ingredients which are useful in the present invention.
[0028] Thus, when a perfume composition which is composed of ingredients having a B.P. of
about 260°C or lower and a ClogP, or an experimental logP, of about 3 or higher, is
used in an detergent composition, the perfume is very effusive and very noticeable
when the product is used. Table 1 gives some non-limiting examples of the preferred
perfume ingredients, useful in the detergent compositions of the present invention.
Particularly preferred perfume oils for encapsulation, include one or a mixture of
more than one ingredient selected from octyl aldehyde, nonyl aldehyde, decyl aldehyde,
dodecyl aldehyde (dodecanal or lauric aldehye), diphenyl oxide, alpha-Ionine, Lilial
and alpha-iso "gamma" methyl Ionone. These have been found to be particularly useful
for masking malodours produced from fatty acid odours. These particularly preferred
perfume oils may be encapsulated singly or as part of a mixture with other preferred
(i.e. listed in Table 1 below) or particularly preferred perfume oils or as part of
a mixture with other perfume oils.
Table I Examples of Preferred Perfume Ingredients
Perfume Ingredients |
Approx. BP(°C) |
Approx. ClogP |
allo-Ocimene |
192 |
4.362 |
Allyl Heptoate |
210 |
3.301 |
Anethol |
236 |
3.314 |
Benzyl Butyrate |
240 |
3.698 |
Camphene |
159 |
4.192 |
Carvacrol |
238 |
3.401 |
beta-Caryophyllene |
256 |
6.333 |
cis-3-Hexenyl Tiglate |
101 |
3.700 |
Citcal (Neral) |
228 |
3.120 |
Citronellol |
225 |
3.193 |
Citronellyl Acetate |
229 |
3.670 |
Citronellyl Isobutyrate |
249 |
4.937 |
Citronellyl Nitrile |
225 |
3.094 |
Citronellyl Propionate |
242 |
4.628 |
Cyclohexyl Ethyl Acetate |
187 |
3.321 |
Decyl Aldehyde |
209 |
4.008 |
Dihydro Myrcenol |
208 |
3.030 |
Dihydromyrcenyl Acetate |
225 |
3.879 |
Dimethyl Octanol |
213 |
3.737 |
Diphenyl Oxide |
252 |
4.240 |
Dodecalactone |
258 |
4.359 |
Ethyl Methyl Phenyl Glycidate |
260 |
3.165 |
Fenchyl Acetate |
220 |
3.485 |
gamma Methyl Ionone |
230 |
4.089 |
gamma-n-Melhyl Ionone |
252 |
4.309 |
gamma-Nonalactone |
243 |
3.140 |
Geranyl Acetate |
245 |
3.715 |
Geranyl Formate |
216 |
3.269 |
Geranyl Isobutymte |
245 |
4.393 |
Geranyl Nitrile |
222 |
3.139 |
Hexenyl Isobutyrate |
182 |
3.181 |
Hexyl Neopentanoate |
224 |
4.374 |
Hexyl Tiglate |
231 |
3.800 |
alpha-lonone |
237 |
3.381 |
beta-Ionone |
239 |
3.960 |
gamma-Ionone |
240 |
3.780 |
alpha-Irone |
250 |
3.820 |
Isobomyl Acetate |
227 |
3.485 |
Isobutyl Benzoate |
242 |
3.028 |
Isononyl Acetate |
200 |
3.984 |
Isononyl Alcohol |
194 |
3.078 |
Isobutyl Quinoline |
252 |
4.193 |
Isomenthol |
219 |
3.030 |
para-Isopropyl Phenylacetaldehyde |
243 |
3.211 |
Isopulegol |
212 |
3.330 |
Lauric Aldehyde (Dodecanal) |
249 |
5.066 |
Lilial (p-t-Bucinal) |
258 |
3.858 |
d-Limonene |
177 |
4.232 |
Linalyl Acetate |
220 |
3.500 |
Menthyl Acetate |
227 |
3.210 |
Methyl Chavicol |
216 |
3.074 |
alpha-iso "gamma" Methyl Ionone |
230 |
4.209 |
Methyl Nonyl Acetaldehyde |
232 |
4.846 |
Methyl Octyl Acetaldehyde |
228 |
4.317 |
Myrcene |
167 |
4.272 |
Neral |
228 |
3.120 |
Neryl Acetate |
231 |
3.555 |
Nonyl Acetate |
212 |
4.374 |
Nonyl Aldehyde |
212 |
3.479 |
Octyl Aldehyde |
223 |
3.845 |
Orange Terpenes (d-Limonene) |
177 |
4.232 |
para-Cymene |
179 |
4.068 |
Phenyl Heptanol |
261 |
3.478 |
Phenyl Hexanol |
258 |
3.299 |
alpha-Pinene |
157 |
4.122 |
beta-Pinene |
166 |
4.182 |
alpha-Terpinene |
176 |
4.412 |
gamma-Terpinene |
183 |
4.232 |
Terpinolene |
184 |
4.232 |
Terpinyl acetate |
220 |
3.475 |
Tetrahydro Linalool |
191 |
3.517 |
Tetrahydro Myrcenol |
208 |
3.517 |
Tonalid |
246 |
6.247 |
Undecenal |
223 |
4.053 |
Veratrol |
206 |
3.140 |
Verdox |
221 |
4.059 |
Vertenex |
232 |
4.060 |
[0029] The perfume oil in the encapsulated perfume particle may be adsorbed or absorbed
onto a carrier prior to encapsulation. Suitable carriers are described in WO97/11151.
A particularly preferred carrier is zeolite.
[0030] The detergent compositions herein comprise from about 0.01 % to 50% of the encapsulated
perfume particle. More preferably, the detergent compositions herein comprise from
0.05% to 8.0% of the perfume particle, even more preferably from 0.5% to 3.0%. Most
preferably, the detergent compositions herein contain from 0.05% to 1.0% of the encapsulated
perfume particle. The encapsulated perfume particles preferably have size of from
1 micron to 1000 microns, more preferably from 50 microns to 500 microns.
[0031] The perfume oil and/or perfume composition is generally present in the detergent
compositions of the invention in amounts of from 0.001% to about 5%, preferably from
0.01% to 5%, and more usually from 0.05% to 3%. Where present in the detergent compositions
of the present invention, the preferred perfume ingredients may comprise 100% of the
perfume oil, but is more usually used in addition to other perfume ingredients. A
mixture of more than one of the preferred perfume ingredients may be present for example,
at least 2 or even at least 5 or 6 or 7 different preferred perfume ingredients. Furthermore,
the encapsulated perfume particles may contain at least 1 Or 5 or 10 wt% or even at
least 20, 30, 40, 50, 60, 70, 80 or 90 wt% of such preferred perfume ingredients.
[0032] Most common perfume ingredients which are derived from natural or synthetic sources
are composed of a multitude of components. For example, orange terpenes contain about
90% to about 95% d-limonene, but also contain many other minor ingredients. When each
such material is used in the formulation of the perfume oils in the present invention,
it is counted as one ingredient, for the purpose of defining the invention.
[0033] The detergent compositions may comprise in addition to the encapsulated perfume oil,
additional perfume oil forming part of the total perfume composition in the detergent
composition. The additional perfume oil may be incorporated into the detergent composition
by any other delivery method, for example, simply by spraying onto the finished detergent
composition or onto a component thereof, prior to mixing to form the finished detergent
composition.
[0034] The encapsulated perfume particles also may comprise perfume oil comprising esters
derived from fatty acids having 1 to 7 carbon atoms. Where the detergent composition
additionally comprises additional perfume oil, preferably at least 60 wt%, or at least
80 or 90 or substantially all the ester derived from fatty acid having from 1 to 7
carbon atoms will be present in the encapsulated perfume particles.
[0035] In a further aspect of the invention, the encapsulated perfume oil and/or the perfume
composition in the detergent composition comprises at least 10 % , 20%, 30%, 40% ,
50%, 60%, 70%, 80%, or even 90% of one or more perfume ingredients having a molecular
weight of greater than 0 but less than or equal to 350 daltons, from about 100 daltons
to about 350 daltons, from about 130 daltons to about 270 daltons, or even from about
140 daltons to about 230 daltons; at least 80%, 85%, 90% or even 95% of said one or
more perfume ingredients having a cLogP of at least 2.4, from about 2.75 to about
8.0 or even from about 2.9 to about 6.0, said perfume composition comprising at least
5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, or even 95% of said one or more perfume
ingredients having a cLogP in the range of at least 2.4, from about 2.75 to about
8.0 or even from about 2.9 to about 6.0. In said aspect of the invention said one
or more perfume ingredients may be selected from the group consisting of a Schiff's
base, ether, phenol, ketone, alcohol, ester, lactone, aldehyde, nitrile, natural oil
or mixtures thereof. Schiff's base and nitriles may be least preferred. In certain
aspects of the invention as recited above, said one or more perfume ingredients may
include Table 2 Perfume Ingredients or mixtures thereof or even Table 2 Perfume Ingredients
1 through 28 or mixtures thereof. It may be preferred for ketones and aldehydes to
have a molecular weight of below 200 daltons.
[0036] In another aspect of the invention said perfume composition comprises at least 10
% , 20%, 30%, 40% , 50%, 60%, 70%, 80%, or even 90% of a perfume ingredient selected
from the group consisting of the ingredients listed in Table 2 below and mixtures
thereof.
Table 2
|
Chemical Name |
CAS |
Functionality |
M Wt |
clogP |
1 |
2-Methoxynaphtlialene |
93-04-9 |
Ether |
158 |
3.24 |
2 |
Diphenyl ether |
101-84-8 |
Ether |
170 |
4.24 |
3 |
2-methoxy-4-propenyl phenol |
120-11-6 |
Phenol |
164 |
4.63 |
4 |
2-Methoxy-4 allyl phenol |
97-53-0 |
Phenol |
164 |
2.40 |
5 |
4-Penten-1-one,1-(5,5-dimethyl-1-cyclohexen-1-yl) |
56973-85-4 |
Ketone |
192 |
4.0 |
6 |
(1alpha (E),2 beta)-1-(2,6,6-Trimethyl-cyclohex-3-en-1-yl)but-2-en-1-one |
71048-82-3 |
Ketone |
192 |
3.62 |
7 |
3-Buten-2-one, 3-Methyl-4-(2,6,6-Trimethyl-2-Cyclohexen-1-yl) |
127-51-5 |
Ketone |
206 |
4.0 |
8 |
2-(2-(4-methyl-3-cyclohexen-1-yl)propyl)cyclopentanone |
95962-14-4 |
Ketone |
220 |
4.44 |
9 |
4-[(2,6,6-trimethyl-1-cyclohex-2-enyl)]but-3-en-2-one |
127-41-3 |
Ketone |
192 |
3.71 |
10 |
1Buten-1-ol,2ethyl-4-(2,2,3-trimethyl-3-cyclopentyl-1- |
28219-61-6 |
Alcohol |
208 |
4.43 |
|
yl)- |
|
|
|
|
11 |
2-Ethyl-4-(2,2,3-trimethylcyclopent-3-enyl-1)-2-buten-1-ol |
28219-61-6 |
Alcohol |
208 |
4.43 |
12 |
Cyclopentaneacetic acid,3oxo-2-pentyl-methyl ester |
24851-98-7 |
Ester |
226 |
2.42 |
13 |
Methyl 2-hexyl-3-oxo-cyclopentanecarboxylate |
37172-53-5 |
Ester |
226 |
3.09 |
14 |
Tricyclodecenyl Propionate |
17511-60-3 |
Ester |
206 |
2.89 |
15 |
Tricyclo Decenyl Acetate |
2500-83-6 |
Ester |
190 |
2.36 |
16 |
n-pentyl salicylate |
2050-08-0 |
Ester |
208 |
4.56 |
17 |
chromen-2-one or 1,2-benzopyrone |
91-64-5 |
Lactone |
146 |
1.41 |
18 |
4-(tricycle(5,2,1,0)decylidene-8)butanal |
30168-23-1 |
Aldehyde |
204 |
3.63 |
19 |
3-(3-isopropylphenyl)butanal |
125109-85-5 |
Aldehyde |
190 |
3.55 |
20 |
p-tert.Butyl-alpha-methyldihydrocinnamic aldehyde |
80-54-6 |
Aldehyde |
204 |
3.86 |
21 |
alpha-Hexylcinnamaldehyde |
101-86-0 |
Aldehyde |
216 |
4.85 |
22 |
n-octanal |
124-13-0 |
Aldehyde |
128 |
2.95 |
23 |
n-nonanal |
124-19-6 |
Aldehyde |
142 |
3.98 |
24 |
n-decanal |
10486-19-8 |
Aldehyde |
156 |
5.60 |
25 |
dodecanal |
112-54-9 |
Aldehyde |
184 |
5.07 |
26 |
Benzene propane nitrile alpha-ethenyl-alpha-methyl |
973 84-48-0 |
Nitrile |
171 |
2.31 |
27 |
2-cyclohexylidene-2-phenylacetonitrile |
104621-98-0 |
Nitrile |
197 |
n/a |
28 |
Patchouli |
n/a |
Natural Oil |
n/a |
n/a |
29 |
Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl- |
3738-00-9 |
Ether |
236 |
5.26 |
30 |
Cyclopentanone, 2-pentyl- |
4819-67-4 |
Ketone |
154 |
2.94 |
31 |
Ethanone, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)- |
54464-57-2 |
Ketone |
234 |
4.84 |
32 |
3-methyl-4(5)-cyclopentadecenone |
82356-51-2 |
Ketone |
236 |
5.60 |
33 |
2(3H)-Furanone, 5-heptyldihydro- |
104-67-6 |
Lactone |
184 |
3.83 |
34 |
Methyl ionone (mixture) |
1335-46-2 |
Ketone |
206 |
4.23 |
35 |
Spiro[1,3-dioxolane-2,8'(5'H)-[2H-2,4a]methanonaphthalene], hexahydro-1',1',5',5'-tetramethyl-,
[2'S-(2'.alpha.,4'a.alpha.,8'a.alpha .)]- |
154171-77-4 |
Ketone |
n/a |
5.67 |
36 |
Undecanal, 2-methyl- |
110-41-8 |
Aldehyde |
184 |
4.85 |
37 |
10-Undecenal |
112-45-8 |
Aldehyde |
168 |
4.05 |
38 |
4-Methyl-3-decen-5-ol |
81782-77-6 |
Alcohol |
170 |
|
39 |
Benzoic acid, 2-hydroxy-, cyclohexyl ester |
25485-88-5 |
Ester |
220 |
4.48 |
40 |
4H-Inden-4-one, 1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl- |
33704-61-9 |
Ketone |
206 |
3.99 |
41 |
N-2,4-Dimethyl-3-cyclohexenemethylene methyl anthranilate |
68738-99-8 |
Schiffs base |
n/a |
4.78 |
42 |
2-Buten-1-ol, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)- |
28219-61-6 |
Alcohol |
208 |
4.43 |
43 |
Acetic acid, hexyl ester |
142-92-7 |
Ester |
144 |
2.83 |
44 |
1,6-Octadien-3-ol, 3,7-dimethyl- |
78-70-6 |
Alcohol |
154 |
2.55 |
45 |
Cyclohexanol, 2-(1,1-dimethylethyl)-, acetate |
88-41-5 |
Ester |
198 |
4.06 |
46 |
2-Butanone, 4-(4-hydroxyphenyl)- |
5471-51-2 |
Ketone |
164 |
1.07 |
47 |
Ethanone, 1-(2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-5-yl)-,
[3R-(3.a1pha,3a.beta,7.beta,8a. alpha.)]- |
32388-55-9 |
Ketone |
246 |
4.75 |
48 |
Cyclododecane, (ethoxymethoxy)- |
58567-11-6 |
Ether |
242 |
5.48 |
49 |
Cyclohexane, 3-ethoxy-1,1,5-trimethyl-, cis- |
24691-15-4 |
Ether |
156 |
3.93 |
50 |
1,3-Benzodioxole-5-carboxaldehyde |
120-57-0 |
Ether/aldehyd e |
150 |
1.14 |
51 |
Benzoic acid, 2-hydroxy-, phenylmethyl ester |
118-58-1 |
Ester |
228 |
4.22 |
52 |
2-Cyclopenten-1-one, 2-methyl-3-(2-pentenyl)- |
11050-62-7 |
Ketone |
164 |
2.64 |
53 |
Oxacyclohexadecen-2-one |
34902-57-3 |
Lactone |
238 |
5.40 |
54 |
4-Cyclopentadecen-1-one, (Z)- |
0014595-54-1 |
Ketone |
222 |
n/a |
55 |
Benzoic acid, 2-[(7-hydroxy-3,7-dimethyloctylidene)amino]-, methyl |
89-43-0 |
Schiffs base |
305 |
4.17 |
56 |
4,7-Methano-3aH-indene-3a-carboxylic acid, octahydro-, ethyl ester, (3a.alpha.,4.beta.,7.beta.,7a.
alpha.)- |
80623-07-0 |
Ester |
209 |
3.37 |
57 |
Benzoic acid, 2-hydroxy-, 3-hexenyl ester, (Z)- |
65405-77-8 |
Ester |
220 |
4.61 |
58 |
Benzoic acid, 2-amino-, methyl ester |
134-20-3 |
Ester |
151 |
2.02 |
59 |
Benzoic acid, 2-hydroxy-, hexyl ester |
6259-76-3 |
Ester |
222 |
5.09 |
60 |
Carbonic acid, 4-cycloocten-1-yl methyl ester |
87731-18-8 |
Ester |
184 |
2.77 |
61 |
5-Cyclohexadecen-1-one |
37609-25-9 |
Ketone |
236 |
5.97 |
62 |
Cyclohexanepropanoic acid, 2-propenyl ester |
705-87-5 |
Ester |
196 |
3.93 |
63 |
Pentanoic acid, 2-methyl-, ethyl ester, (S)- |
28959-02-6 |
Ester |
144 |
2.61 |
64 |
3-Buten-2-one, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (E)- |
79-77-6 |
Ketone |
192 |
3.77 |
65 |
1,3-Dioxolane, 2,4-dimethyl-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-,
cis- |
131812-51-6 |
Ether |
288 |
6.27 |
66 |
2,6-Octadienenitrile, 3,7-dimethyl- |
5146-66-7 |
Nitrile |
227 |
3.25 |
67 |
2,6-Nonadienenitrile, 3,7-dimethyl- |
61792-11-8 |
Nitrile |
163 |
3.78 |
68 |
3-Cyclohexene-1-carboxaldehyde, dimethyl- |
27939-60-2 |
Aldehyde |
138 |
2.53 |
69 |
Oxacyclohexadecan-2-one |
106-02-5 |
Lactone |
240 |
6.29 |
70 |
Methy-2-methyl-3-(4-tert butylphenyl)propylidenanthr anilate |
91-51-0 |
Schiffs base |
337 |
6.31 |
71 |
Acetic acid, (3-methylbutoxy)-, 2-propenyl ester |
67634-00-8 |
Ester |
186 |
2.38 |
72 |
9-Undecenal, 2,6,10-trimethyl- |
141-13-9 |
Aldehyde |
210 |
5.16 |
73 |
Cyclopentanone, 3-methyl-2-pentyl- |
13074-63-0 |
Ketone |
168 |
3.46 |
[0037] In any of the aforementioned aspects, if the perfume oil or composition comprises
an ester perfume ingredient, when said perfume oil or composition comprises an ester
perfume component said ester perfume may have one or more of the following characteristics:
branching or pendant rings in at least one of the alpha, beta or gamma positions;
branching or pendant rings in at least one of the alpha or beta positions; or at least
one tertiary carbon atom in the alpha position. While not being bound by theory, it
is believed that the aforementioned perfume ester characteristics result in increased
perfume ester stability, and thus perfume composition stability, when said perfume
ester in is the presence of an enzyme that can hydrolyze ester bonds, for example,
enzymes classed in EC 3.1.1. such as lipases.
[0038] In any of the aforementioned aspects of the invention, said perfume oil or composition
typically contains no more than about 5 %, or even none of the perfume components
selected from the group consisting of Acetic acid, phenylmethyl ester; Benzene ethanol;
Butanoic acid, 2-methyl-, ethyl ester; 4H-Pyran-4-one, 2-ethyl-3-hydroxy-; Benzaldehyde,
4-hydroxy-3-methoxy-; Benzaldehyde, 3-ethoxy-4-hydroxy-; 3-Hexen-1-ol, acetate, (Z)-;
Butanoic acid, 2-methyl-, 1-; methylethyl ester; 3-Decanone, 1-hydroxy-; 2-Heptanone;
Benzaldehyde; Propanenitrile, 3-(3-hexenyloxy)-, (Z)-; 2-Butanone, 4-phenyl-; 2-Hexen-l-ol;
2(3H)-Furanone, 5-butyldihydro-,
Processes of Making Perfume Compositions
[0039] Perfume compositions of the present invention may be made by ad-mixing of perfume
raw materials, which are typically liquids. Certain perfume raw materials are solid
materials and can require gentle heat to homogenise with the rest of the perfume.
The perfume blend can also comprise a significant proportion of a diluent (e.g dipropylene
glycol), an antioxidant or a solubilising material. Solubilisers can be particularly
advantageous where the surfactant level is low in order to disperse the perfume in
a predominantly hydrophilic matrix such as aqueous liquid cleaners.
Perfume Delivery Methods
[0040] Any of the aforementioned aspects of the perfume compositions may be combined with
other materials to produce any of the following delivery systems for delivering additional
perfume oils into the detergent composition: spray-on perfume oils, sprayed directly
onto detergent composition or components thereof, starch encapsulate delivery systems,
porous carrier material delivery systems, coated porous carrier material delivery
systems, microencapsulate delivery systems. Preferably, detergent cornopositions of
the invention will comprise encapsulates and spray-on perfume. Suitable methods of
producing the aforementioned delivery systems may be found in one or more of the following
U.S. patents 6,458,754; 5,656,584; 6,172,037; 5,955,419 and 5,691,383 and WIPO publications
WO 94/28017, WO 98/41607, WO 98/52527. Such delivery systems may be used alone, in
combination with other or even in combination with the neat sprayed on or admixed
perfume compositions of the present invention in a consumer product.
[0041] In addition to the lipase enzyme and encapsulated perfume particles, the detergent
compositions of the invention will also contain one or more conventional detergent
ingredients and/or detergent adjunct ingredients.
Optional Detersive Adjuncts
[0042] The detergent compositions of the invention may be in any convenient form such as
powdered or granular solids, bars, tablets or non-aqueous liquids, including gel and
paste forms. Other forms of cleaning composition include other institutional and/or
household cleaning compositions such as liquid or solid cleaning and disinfecting
agents, including antibacterial cleaners car or carpet shampoos, denture cleaners,
hard surface cleaners, for example for kitchen and/or bathroom use optionally for
cleaning metal, hair shampoos, shower gels, bath foam as well as cleaning auxiliaries
such as bleach additives and "stain stick" or pre-treat types. When present in the
granular form the detergent compositions of the present invention are preferably those
having an overall bulk density of from 350 to 1200 g/l, more preferably 450 to 1000g/l
or even 500 to 900g/l. Preferably, the detergent particles of the detergent composition
in a granular form have a size average particle size of from 200µm to 2000µm, preferably
from 350µm to 600µm.
[0043] Generally the detergent compositions of the invention will be mixed with other detergent
particles including combinations of agglomerates, spray-dried powders and/or dry added
materials such as bleaching agents, enzymes etc.
[0044] As a preferred embodiment, the conventional detergent ingredients are selected from
typical detergent composition components such as detersive surfactants and detersive
builders- Optionally, the detergent ingredients can include one or more other detersive
adjuncts or other materials for assisting or enhancing cleaning performance, treatment
of the substrate to be cleaned, or to modify the aesthetics of the detergent composition.
Usual detersive adjuncts of detergent compositions include the ingredients set forth
in U.S. Pat. No. 3,936,537, Baskerville et al. and in Great Britain Patent Application
No. 9705617.0, Trinh et al., published September 24, 1997. Such adjuncts are included
in detergent compositions at their conventional art-established levels of use, generally
from 0% to about 80% of the detergent ingredients, preferably from about 0.5% to about
20% and can include color speckles, suds boosters, suds suppressors, antitarnish and/or
anticorrosion agents, soil-suspending agents, soil release agents, dyes, fillers,
optical brighteners, germicides, alkalinity sources, hydrotropes, antioxidants, enzymes,
enzyme stabilizing agents, solvents, solubilizing agents, chelating agents, clay soil
removal/anti-redeposition agents, polymeric dispersing agents, processing aids, fabric
softening components, static control agents, bleaching agents, bleaching activators,
bleach stabilizers, etc.
[0045] As described above, detergent compositions comprising the particles of the invention
will comprise at least some of the usual detergent adjunct materials, such as agglomerates,
extrudates, other spray dried particles having different composition to those of the
invention, or dry added materials. Conventionally, surfactants are incorporated into
agglomerates, extrudates or spray dried particles along with solid materials, usually
builders, and these may be admixed with the spray dried particles of the invention.
However, as described above some or all of the solid material may be replaced with
the particles of the invention.
[0046] The detergent adjunct materials are typically selected from the group consisting
of detersive surfactants, builders, polymeric co-builders, bleach, chelants, enzymes,
anti-redeposition polymers, soil-release polymers, polymeric soil-dispersing and/or
soil-suspending agents, dye-transfer inhibitors, fabric-integrity agents, suds suppressors,
fabric-softeners, flocculants, perfumes, whitening agents, photobleach and combinations
thereof.
[0047] The precise nature of these additional components, and levels of incorporation thereof
will depend on the physical form of the composition or component, and the precise
nature of the washing operation for which it is to be used.
[0048] A highly preferred adjunct component is a surfactant. Preferably, the detergent composition
comprises one or more surfactants. Typically, the detergent composition comprises
(by weight of the composition) from 0% to 50%, preferably from 5% and more preferably
from 10 or even 15 wt% to 40%, or to 30%, or to 20% one or more surfactants. Preferred
surfactants are anionic surfactants, non-ionic surfactants, cationic surfactants,
zwitterionic surfactants, amphoteric surfactants, cationic surfactants and mixtures
thereof.
[0049] Preferred anionic surfactants comprise one or more moieties selected from the group
consisting of carbonate, phosphate, sulphate, sulphonate and mixtures thereof. Preferred
anionic surfactants are C
8-18 alkyl sulphates and C
8-18 alkyl sulphonates. Suitable anionic surfactants incorporated alone or in mixtures
in the compositions of the invention are also the C
8-18 alkyl sulphates and/or C
8-18 alkyl sulphonates optionally condensed with from 1 to 9 moles of C
1-4 alkylene oxide per mole of C
8-18 alkyl sulphate and/or C
8-18 alkyl sulphonate. The alkyl chain of the C
8-18 alkyl sulphates and/or C
8-18 alkyl sulphonates may be linear or branched, preferred branched alkyl chains comprise
one or more branched moieties that are C
1-6 alkyl groups. Other preferred anionic surfactants are C
8-18 alkyl benzene sulphates and/or C
8-18 alkyl benzene sulphonates. The alkyl chain of the C
8-18 alkyl benzene sulphates and/or C
8-18 alkyl benzene sulphonates may be linear or branched, preferred branched alkyl chains
comprise one or more branched moieties that are C
1-6 alkyl groups.
[0050] Other preferred anionic surfactants are selected from the group consisting of: C
8-18 alkenyl sulphates, C
8-18 alkenyl sulphonates, C
8-18 alkenyl benzene sulphates, C
8-18 alkenyl benzene sulphonates, C
8-18 alkyl di-methyl benzene sulphate, C
8-18 alkyl di-methyl benzene sulphonate, fatty acid ester sulphonates, di-alkyl sulphosuccinates,
and combinations thereof. The anionic surfactants may be present in the salt form.
For example, the anionic surfactant may be an alkali metal salt of one or more of
the compounds selected from the group consisting of: C
8-18 alkyl sulphate, C
8-18 alkyl sulphonate, C
8-18 alkyl benzene sulphate, C
8-C
18 alkyl benzene sulphonate, and combinations thereof. Preferred alkali metals are sodium,
potassium and mixtures thereof. Typically, the detergent composition comprises from
10% to 30wt% anionic surfactant.
[0051] Preferred non-ionic surfactants are selected from the group consisting of: C
8-18 alcohols condensed with from 1 to 9 of C
1-C
4 alkylene oxide per mole of C
8-18 alcohol, C
8-18 alkyl N-C
1-4 alkyl glucamides, C
8-18 amido C
1-4 dimethyl amines, C
8-18 alkyl polyglycosides, glycerol monoethers, polyhydroxyamides, and combinations thereof.
Typically the detergent compositions of the invention comprises from 0 to 15, preferably
from 2 to 10 wt% non-ionic surfactant.
[0052] Preferred cationic surfactants arc quaternary ammonium compounds. Preferred quaternary
ammonium compounds comprise a mixture of long and short hydrocarbon chains, typically
alkyl and/or hydroxyalkyl and/or alkoxylated alkyl chains. Typically, long hydrocarbon
chains are C
8-18 alkyl chains and/or C
8-18 hydroxyalkyl chains and/or C
8-18 alkoxylated alkyl chains. Typically, short hydrocarbon chains are C
1-4 alky chains and/or C
1-4 hydroxyabcyl chains and/or C
1-4 alkoxylated alkyl chains. Typically, the detergent composition comprises (by weight
of the composition) from 0% to 20% cationic surfactant.
[0053] Preferred zwitterionic surfactants comprise one or more quaternized nitrogen atoms
and one or more moieties selected from the group consisting of: carbonate, phosphate,
sulphate, sulphonate, and combinations thereof. Preferred zwitterionic surfactants
are alkyl betaines. Other preferred zwitterionic surfactants are alkyl amine oxides.
Catanionic surfactants which are complexes comprising a cationic surfactant and an
anionic surfactant may also be included. Typically, the molar ratio of the cationic
surfactant to anionic surfactant in the complex is greater than 1:1, so that the complex
has a net positive charge.
[0054] A further preferred adjunct component is a builder. Preferably, the detergent composition
comprises (by weight of the composition and on an anhydrous basis) from 20% to 50%
builder. Preferred builders are selected from the group consisting of: inorganic phosphates
and salts thereof, preferably orthophosphate, pyrophosphate, tri-poly-phosphate, alkali
metal salts thereof, and combinations thereof; polycarboxylic acids and salts thereof,
preferably citric acid, alkali metal salts of thereof, and combinations thereof; aluminosilicates,
salts thereof, and combinations thereof, preferably amorphous aluminosilicates, crystalline
aluminosilicates, mixed amorphous/crystalline aluminosilicates, alkali metal salts
thereof, and combinations thereof, most preferably zeolite A, zeolite P, zeolite MAP,
salts thereof, and combinations thereof; silicates such as layered silicates, salts
thereof, and combinations thereof, preferably sodium layered silicate; and combinations
thereof.
[0055] A preferred adjunct component is a bleaching agent. Preferably, the detergent composition
comprises one or more bleaching agents. Typically, the composition comprises (by weight
of the composition) from 1% to 50% of one or more bleaching agent. Preferred bleaching
agents are selected from the group consisting of sources of peroxide, sources of peracid,
bleach boosters, bleach catalysts, photo-bleaches, and combinations thereof. Preferred
sources of peroxide are selected from the group consisting of: perborate monohydrate,
perborate tetra-hydrate, percarbonate, salts thereof, and combinations thereof. Preferred
sources of peracid are selected from the group consisting of: bleach activator typically
with a peroxide source such as perborate or percarbonate, preformed peracids, and
combinations thereof. Preferred bleach activators are selected from the group consisting
of: oxy-benzene-sulphonate bleach activators, lactam bleach activators, imide bleach
activators, and combinations thereof. A preferred source of peracid is tetra-acetyl
ethylene diamine (TAED)and peroxide source such as percarbonate. Preferred oxy-benzene-sulphonate
bleach activators are selected from the group consisting of: nonanoyl-oxy-benzene-sulponate,
6-nonamido-caproyl-oxy-benzene-sulphonate, salts thereof, and combinations thereof.
Preferred lactam bleach activators are acyl-caprolactams and/or acyl-valerolactams.
A preferred imide bleach activator is N-nonanoyi-N-n-iethyl-acetamide.
[0056] Preferred preformed peracids are selected from the group consisting of N,N-pthaloyl-amino-peroxycaproic
acid, nonyl-amido-peroxyadipic acid, salts thereof, and combinations thereof. Preferably,
the STW-composition comprises one or more sources of peroxide and one or more sources
of peracid. Preferred bleach catalysts comprise one or more transition metal ions.
Other preferred bleaching agents are di-acyl peroxides. Preferred bleach boosters
are selected from the group consisting of: zwitterionic imines, anionic imine polyions,
quaternary oxaziridinium salts, and combinations thereof. Highly preferred bleach
boosters are selected from the group consisting of: aryliminium zwitterions, aryliminium
polyions, and combinations thereof. Suitable bleach boosters are described in US360568,
US5360569 and US5370826.
[0057] A preferred adjunct component is an anti-redeposition agent Preferably, the detergent
composition comprises one or more anti-redeposition agents. Preferred anti-redeposition
agents are cellulosic polymeric components, most preferably carboxymethyl celluloses.
[0058] A preferred adjunct component is a chelant. Preferably, the detergent composition
comprises one or more chelants. Preferably, the detergent composition comprises (by
weight of the composition) from 0.01% to 10% chelant. Preferred chelants are selected
from the group consisting of: hydroxyethane-dimethylene-phosphonic acid, ethylene
diamine tetra(methylene phosphonic) acid, diethylene triamine pentacetate, ethylene
diamine tetraacetate, diethylene triamine penta(methyl phosphonic) acid, ethylene
diamine disuccinic acid, and combinations thereof
[0059] A preferred adjunct component is a dye transfer inhibitor. Preferably, the detergent
composition comprises one or more dye transfer inhibitors. Typically, dye transfer
inhibitors are polymeric components that trap dye molecules and retain the dye molecules
by suspending them in the wash liquor. Preferred dye transfer inhibitors are selected
from the group consisting of: polyvinylpyrrolidon.es, polyvinylpyridine N-oxides,
polyvinylpyrrolidone-polyvinylimidazole copolymers, and combinations thereof.
[0060] Preferred adjunct components include other enzymes. Preferably, the detergent composition
comprises one or more additional enzymes. Preferred enzymes are selected from then
group consisting of: amylases, arabinosidases, carbohydrases, cellulases, chondroitinases,
cutinases, dextranases, esterases, β-glucanases, gluco-amylases, hyaluronidases, keratanases,
laccase, ligninases, lipoxygenases, malanases, mannanases, oxidases, pectinases, pentosanases,
peroxidases, phenoloxidases, phospholipases, proteases, pullulanases, reductases,
tannases, transferases, xylanases, xyloglucanases, and combinations thereof. Preferred
additional enzymes are selected from the group consisting of: amylases, carbohydrases,
cellulases, proteases, and combinations thereof.
[0061] A preferred adjunct component is a fabric integrity agent. Preferably, the detergent
composition comprises one or more fabric integrity agents. Typically, fabric integrity
agents are polymeric components that deposit on the fabric surface and prevent fabric
damage during the laundering process. Preferred fabric integrity agents are hydrophobically
modified celluloses. These hydrophobically modified celluloses reduce fabric abrasion,
enhance fibre-fibre interactions and reduce dye loss from the fabric. A preferred
hydrophobically modified cellulose is described in WO99/14245. Other preferred fabric
integrity agents are polymeric components and/or oligomeric components that are obtainable,
preferably obtained, by a process comprising the step of condensing imidazole and
epichlorhydrin.
[0062] A preferred adjunct component is a salt. Preferably, the detergent composition comprises
one or more salts. The salts can act as alkalinity agents, buffers, builders, co-builders,
encrustation inhibitors, fillers, pH regulators, stability agents, and combinations
thereof. Typically, the detergent composition comprises (by weight of the composition)
from 5% to 60% salt. Preferred salts are alkali metal salts of aluminate, carbonate,
chloride, bicarbonate, nitrate, phosphate, silicate, sulphate, and combinations thereof.
Other preferred salts are alkaline earth metal salts of aluminate, carbonate, chloride,
bicarbonate, nitrate, phosphate, silicate, sulphate, and combinations thereof. Especially
preferred salts are sodium sulphate, sodium carbonate, sodium bicarbonate, sodium
silicate, sodium sulphate, and combinations thereof. Optionally, the alkali metal
salts and/or alkaline earth metal salts may be anhydrous.
[0063] A preferred adjunct component is a soil release agent. Preferably, the detergent
composition comprises one or more soil release agents. Typically, soil release agents
are polymeric compounds that modify the fabric surface and prevent the redeposition
of soil on the fabric. Preferred soil release agents are copolymers, preferably block
copolymers, comprising one or more terephthalate unit. Preferred soil release agents
are copolymers that are synthesised from dimethylterephthalate, 1,2-propyl glycol
and methyl capped polyethyleneglycol. Other preferred soil release agents are anionically
end capped polyesters.
[0064] A preferred adjunct component is a soil suspension agent. Preferably, the detergent
composition comprises one or more soil suspension agents. Preferred soil suspension
agents are polymeric polycarboxylates. Especially preferred are polymers derived from
acrylic acid, polymers derived from maleic acid, and co-polymers derived from maleic
acid and acrylic acid. In addition to their soil suspension properties, polymeric
polycarboxylaces are also useful co-builders for laundry detergents. Other preferred
soil suspension agents are alkoxylated polyalkylene imines. Especially preferred alkoxylated
polyalkylene imines are ethoxylated polyethylene imines, or ethoxylated-propoxylated
polyethylene imine. Other preferred soil suspension agents are represented by the
formula:
bis((C
2H
5O)(C
2H
4O)
n(CH
3)-N
+-C
xH
2x-N
+-(CH
3)-bis((C
2H
4O)
n(C
2H
5O)),
wherein, n=from 10 to 50 and x=from 1 to 20. Optionally, the soil suspension agents
represented by the above formula can be sulphated and/or sulphonated.
Softening system
[0065] The detergent compositions of the invention may comprise softening agents for softening
through the wash such as clay optionally also with flocculant and enzymes.
[0066] Further more specific description of suitable detergent components can be found in
WO97/11151.
Washing Method
[0067] The invention also includes methods of washing textiles comprising cleaning, treating
and/or masking the odour of a situs for example, a surface or fabric. Such method
comprises contacting the situs such as a textile with an aqueous solution comprising
the detergent composition of the invention. The invention may be particularly beneficial
at low water temperatures such as below 30°C or below 25 or 20°C. Typically the aqueous
wash liquor will comprise at least 100 ppm, or at least 500ppm of the detergent composition
Example 1: Perfume Compositions
Common Name |
CAS |
Composition |
|
|
1 |
2 |
3 |
4 |
Yard Yara |
93-04-9 |
5 |
|
|
|
Diphenyl Oxide |
101-84-8 |
2 |
7 |
|
5 |
Iso Eugenol |
120-11-6 |
|
|
6 |
|
Eugenol |
97-53-0 |
|
|
4 |
5 |
Dynascone® |
56973-85-4 |
1 |
1.5 |
|
|
Delta damascone |
71048-82-3 |
2 |
|
4 |
|
Ionone Gamma Methyl |
127-51-5 |
|
|
20 |
5 |
Nectaryl |
95962-14-4 |
20 |
|
|
|
lonone alpha |
127-41-3 |
|
|
4 |
|
Dartanol |
28219-61-6 |
|
|
8 |
|
Levosandol® |
28219-61-6 |
|
|
8 |
|
Hedione® |
24851-98-7 |
|
25 |
|
40 |
Dihydro |
37172-53-5 |
|
10 |
12 |
5 |
IsoJasmonate® |
|
|
|
|
|
Frutene |
17511-60-3 |
25 |
|
|
|
Flor Acetate |
2500-83-6 |
25 |
|
|
|
Amyl Salicylate |
2050-08-0 |
|
20 |
|
|
Coumarin |
91-64-5 |
|
|
4 |
|
Dupical |
30168-23-1 |
|
1 |
|
|
Florhydral® |
125109-85-5 |
|
2 |
|
|
Lilial |
80-54-6 |
|
20 |
20 |
|
Hexyl Cinnamlc aldehyde |
101-86-0 |
|
|
|
40 |
Aldehyde C10 |
10486-19-8 |
5 |
|
|
|
Lauric Aldehyde |
112-54.9 |
|
1.5 |
|
|
Peonile® |
104621-98-0 |
15 |
12 |
|
|
Patchouli |
|
|
|
10 |
|
Balance |
|
100 |
100 |
100 |
100 |
Example 2: Perfumes Made With Compositions from Example 1.
|
|
Perfume Example |
Common Name |
CAS |
A |
B |
C |
D |
Composition 1 |
n/a |
61 |
|
|
|
Composition 2 |
n/a |
|
45 |
|
|
Composition 3 |
n/a |
|
|
26 |
|
Composition 4 |
n/a |
|
|
|
10 |
Cetalox |
3738-00-9 |
|
0.5 |
|
|
Delphone |
4819-67-4 |
|
|
|
2 |
Delta Muscenone |
82356-51-2 |
|
|
1 |
|
Undecalactone |
104-67-6 |
1 |
|
|
|
Aldehyde MNA |
110-41-8 |
2 |
|
|
|
Undecavertal |
81782-77-6 |
|
2 |
|
|
Cyclohexyl salicylate |
25485-88-5 |
|
3 |
|
|
Cashmeran® |
33704-61-9 |
|
|
1 |
|
Agrumea |
6873 8-99-8 |
|
|
3 |
|
Hexyl Acetate |
142-92-7 |
5 |
|
|
|
Verdox |
88-41-5 |
10 |
|
|
|
Methyl Cedrylone |
32388-55-9 |
|
2 |
|
|
Heliotropin |
120-57-0 |
|
|
1 |
|
Benzyl Salicylate |
118-58-1 |
|
|
4 |
|
Iso Jasmone |
11050-62-7 |
|
|
|
1 |
Habanolide® |
34902-57-3 |
|
|
5 |
5 |
Aurantiol |
89-43-0 |
|
|
|
1 |
Cis-3-hexenyl salicylate |
65405-77-8 |
|
3 |
|
|
Methyl Anthranilate |
134-20-3 |
1 |
|
|
|
Hexyl Salicylate |
6259-76-3 |
|
4 |
|
|
Manzanate |
28959-02-6 |
1 |
|
|
|
Geranyl Nitrile |
5146-66-7 |
2 |
|
|
|
Ligustral |
27939-60-2 |
1 |
2 |
|
|
Allyl Amyl Glycolate |
67634-00-8 |
|
1 |
|
|
Adoxal |
141-13-9 |
|
0.5 |
|
|
Jasmylone |
13074-63-0 |
|
|
|
1 |
Benzyl Acetate |
140-11-4 |
|
|
10 |
58 |
Phenyl Ethyl Alcohol |
60-12-8 |
|
34 |
|
|
Vanillin |
121-33-5 |
|
|
1 |
|
Ethyl Vanillin |
121-32-4 |
|
|
0.5 |
|
Cis 3 hexenyl acetate |
3681-71-8 |
|
1 |
|
|
Cinnamalva |
1885-38-7 |
|
|
1 |
|
Benzyl Acetone |
2550-26-7 |
|
|
20 |
20 |
Beta Gamma Hexenol |
2305-21-7 |
1 |
2 |
|
1 |
Gamma Octalactone |
104-50-7 |
|
|
0.5 |
1 |
D-Limonene |
138-86-3 |
15 |
|
26 |
|
Total |
|
I 100 I |
100 |
100 |
100 I |
[0068] In the following encapsulation and detergent compositions the perfume component is
a perfume according to the present invention and/or Examples 1 and 2 above.
Manufacture of Modified Starch Encapsulated Perfume Particles
Example 3
[0069] 1. 225 g of CAPSUL modified starch (National Starch & Chemical) is added to 450 g
of water at 24°C.
2. The mixture is agitated at 600 RPM (turbine impeller 2 inches in diameter) for
20 minutes.
3. 75 g perfume oil is added near the vortex of the starch solution.
4. The emulsion formed is agitated for an additional 20 minutes (at 600 RPM).
5. Upon achieving a perfume droplet size of less than 15 microns, the emulsion is
pumped to a spray drying tower and atomized through a spinning disk with co-current
airflow for drying. The inlet air temperature is set at 205-210°C, the exit air temperature
is stabilized at 98-103°C.
6. Dried particles of the starch encapsulated perfume oil are collected at the dryer
outlet. Analysis of the finished perfume particle (all % based on weight):
Total Perfume Oil |
24.56% |
|
Encapsulated Oil/ Free or Surface Oil |
24.46%/0.10% |
|
Starch |
72.57% |
Moisture |
2.87% |
Particle Size Distribution |
|
|
< 50 micrometers |
16% |
|
50-500 micrometers |
83% |
|
> 500 micrometers |
1% |
Example 4
[0070] In a suitable container 500g of HiCap 100 modified starch (supplied by National Starch
& Chemical) are dissolved into 1000g of deionised water. Once a homogenous solution
is achieved, 40g of anhydrous citric acid is added to the starch solution. The mixture
is agitated for 10 minutes to dissolve the citric acid. At this point, 600g of perfume
is added to the mixture. The emulsion is then agitated with a high shear mixer (ARD-Barico)
for 10 more minutes.
The mixture is then spray dried in a Production Minor cocurrent spray dryer manufactured
by Niro A/S. A rotary atomising disc type FS 1, also from Niro A/S, is used. The air
inlet temperature is 200°C and the outlet temperature 90°C. Disc speed is set at 28,500
rpm. The tower is stabilized at these conditions by spraying water for 30 minutes
before spray drying the emulsion. The dried particles are collected in a cyclone.
[0071] Detergent compositions comprising the encapsulated perfumes of examples 3 and 4 are
exemplified in Table 3 below:
Table 3
Ingredient |
A |
B |
C |
D |
E |
Sodium linear C11-13 alkylbenzene sulfonate |
11% |
12% |
10% |
18% |
15% |
R2N+(CH3)2(C2H4OH), wherein R2 = C12-14 alkyl group |
0.6% |
1% |
|
|
0.6% |
Mid chain methyl branched sodium C12-C14 linear alkyl sulfate |
1.4% |
1.2% |
1% |
|
|
Sodium C12-18 linear alkyl sulfate |
0.7% |
0.5% |
|
|
|
C12-18 linear alkyl ethoxylate condensed with an average of 3-9 moles of ethylene oxide
per mole of alkyl alcohol |
1% |
4% |
2% |
3% |
1% |
Citric acid |
2% |
1.5% |
|
|
2% |
Sodium tripolyphosphate |
|
|
|
25% |
22% |
(anhydrous weight given) |
|
|
|
|
|
Sodium carboxymethyl cellulose |
0.2% |
0.2% |
|
0.3% |
|
Sodium polyacrylate polymer having a weight average molecular weight of from 3000
to 5000 |
2.0% |
0.5% |
1% |
|
0.7% |
Copolymer of maleic/acrylic acid, having a weight average molecular weight of from
50,000 to 90,000, wherein the ratio of maleic to acrylic acid is from 1:3 to 1:4 (Sokalan
CP5 from BASF) |
2.1% |
3.5% |
7% |
2.0% |
2.1% |
Diethylene triamine pentaacetic acid |
0.2% |
|
1.0% |
0.2% |
0.3% |
Ethylene diamine dis1iccinic acid |
|
0.5% |
|
0.6% |
0.5% |
Proteolytic enzyme having an enzyme activity of from 15 mg/g to 70 mg/g |
0.2% |
0.2% |
0.5% |
0.4% |
0.3% |
Amyolitic enzyme having an enzyme activity of from 25 mg/g to 50 mg/g |
0.2% |
0.2% |
0.3% |
0.4% |
0.3% |
Lipex® enzyme from Novozymes having an enzyme activity of 5 mg/g to 25 mg/g |
0.2% |
0.5% |
0.1% |
0.5% |
0.3% |
Anhydrous sodium perborate monohydrate |
|
|
20% |
5% |
8% |
Sodium percarbonate |
10% |
12% |
|
|
|
Magnesium sulfate |
0.1 % |
0.5% |
|
|
|
Nonanoyl oxybenzene sulfonate |
|
|
|
2% |
1.2% |
Tetraacetylethylenediamine |
3% |
4% |
2% |
0.6% |
0.8% |
Brightener |
0.1% |
0.1% |
0.2% |
0.1% |
0.1% |
Sodium carbonate |
10% |
10% |
10% |
19% |
22% |
Sodium sulfate |
20% |
15% |
5% |
5% |
6% |
Zeolite A |
25% |
20% |
20% |
17% |
14% |
Sodium silicate (2.0 R) |
|
0.2% |
|
1% |
1% |
Crystalline layered silicate |
3% |
5% |
10% |
|
|
Photobleach |
0.002% |
|
|
|
|
Polyethylene oxide having a weight average molecular weight from 100 to 10,000 |
2% |
1% |
|
|
|
Perfume spray-on |
0.2% |
0.5% |
0.25% |
0.1% |
|
Starch encapsulated perfume from example 1 or example 2 |
0.4% |
0.5% |
1% |
0.4% |
1.5% |
Silicone based suds suppressor |
0.05% |
0.05% |
|
|
0.02% |
Soap |
|
1.2% |
1.5% |
1.0% |
|
Miscellaneous and moisture |
To 100% |
To 100% |
To 100% |
To 100% |
To 100% |