(19)

(11)

EP 1 663 106 A2

(12)

(88) Date of publication A3: 09.06.2005 (43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04762305.3 (22) Date of filing: 31.08.2004

(51) International Patent Classification (IPC):  A61K 6/00(1980.01) (86) International application number: PCT/CZ2004/000053 (87) International publication number: WO 2005/020876 (10.03.2005 Gazette 2005/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: HR (30) Priority: 02.09.2003 CZ 20032367 (71) Applicant: Pliva-Lachema A.S. 621 33 Brno (CZ)	(72) Inventors: ZALUDEK, Borek 621 00 Brno (CZ) BOLESLAV, Jan 666 01 Tisnov (CZ) KYSILKA, Vladimir 621 00 Brno (CZ) VERNER, Jiri 635 00 Brno (CZ) BRZOBOHATA, Hana 612 00 Brno (CZ) MATEJKOVA, Bozena 635 00 Brno (CZ) KAKRDA, Milan 635 00 Brno (CZ) (74) Representative: Hak, Roman  Traplova, Hakr, Kubat Law and Patent Offices Pristavni 24 CZ-170 00 Praha 7 CZ-170 00 Praha 7 (CZ)