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EP 1 663 205 A1

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(43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04766644.1 (22) Date of filing: 31.08.2004

(51) International Patent Classification (IPC):  A61K 31/415(1985.01) A61K 31/4439(2000.01) A61P 25/00(2000.01) A61K 31/4155(2000.01) A61P 3/04(2000.01) (86) International application number: PCT/EP2004/051961 (87) International publication number: WO 2005/020988 (10.03.2005 Gazette 2005/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 02.09.2003 EP 03019939 (71) Applicant: Solvay Pharmaceuticals GmbH 30173 Hannover (DE)

(72) Inventors: ANTEL, Jochen 31848 Bad Münder (DE) KRAUSE, Günter 31303 Burgdorf (DE) LANGE, Josephus, Hubertus, Maria NL-1325 LP Almere (NL) KRUSE, Cornelis, Gerrit NL-3816 BJ Amersfoort (NL) GREGORY, Peter-Colin 30559 Hannover (DE) DEN BESTEN, Cathaline NL-1396 JP Baambrugge (NL) (74) Representative: Gosmann, Martin et al Solvay Pharmaceuticals GmbH Hans-Böckler-Allee 20 30173 Hannover 30173 Hannover (DE)