(19)

(11)

EP 1 663 295 A2

(12)

(88) Date of publication A3: 30.06.2005 (43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04762796.3 (22) Date of filing: 31.08.2004

(51) International Patent Classification (IPC):  A61K 38/26(1995.01) A61K 47/18(1990.01) A61K 9/08(1974.07) (86) International application number: PCT/DK2004/000576 (87) International publication number: WO 2005/021022 (10.03.2005 Gazette 2005/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 01.09.2003 DK 200301239 08.09.2003 US 501157 P (71) Applicant: NOVO NORDISK A/S 2880 Bagsvaerd (DK)	(72) Inventors: SCHLEIN, Morten DK-2300 K benhavn S (DK) LUDVIGSEN, Svend DK-3540 Lynge (DK) (74) Representative: Noergaard, Torsten et al c/o Novo Nordisk A/S Novo Allé 2880 Bagsvaerd 2880 Bagsvaerd (DK)