(19)

(11)

EP 1 663 311 A2

(12)

(88) Date of publication A3: 11.08.2005 (43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04781993.3 (22) Date of filing: 19.08.2004

(51) International Patent Classification (IPC):  A61K 45/06(1985.01) A61K 31/498(2000.01) A61K 31/517(2000.01) A61K 31/4168(2000.01) A61K 31/135(1985.01) A61K 31/506(2000.01) (86) International application number: PCT/US2004/027415 (87) International publication number: WO 2005/034998 (21.04.2005 Gazette 2005/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 12.09.2003 US 502327 P 30.06.2004 US 881761 (71) Applicant: ALLERGAN, INC. Irvine, California 92612 (US)	(72) Inventors: DONELLO, John, E. Dana Point, CA 92629 (US) GIL, Daniel, W. Corona Del Mar, CA 92625 (US) (74) Representative: HOFFMANN EITLE  Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)