(19)

(11)

EP 1 664 000 A1

(12)

(43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04762824.3 (22) Date of filing: 10.09.2004

(51) International Patent Classification (IPC):  C07D 261/12(1985.01) A61P 31/00(2000.01) A61K 31/42(1985.01) (86) International application number: PCT/DK2004/000604 (87) International publication number: WO 2005/026133 (24.03.2005 Gazette 2005/12)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 12.09.2003 DK 200301323 15.09.2003 US 503104 P (71) Applicant: Arpida A/S 1800 Frederiksberg C (DK)	(72) Inventors: CALI, Patrizia DK-2300 Copenhagen S (DK) HJELMENCRANTZ, Anders SE-216 20 Malmö (SE) NAERUM, Lars DK-2900 Hellerup (DK) (74) Representative: Johansen, Marianne  Albihns A/S, H.C. Andersens Boulevard 49 1553 Copenhagen V 1553 Copenhagen V (DK)