Antitumoral compounds based on Kahalalide F

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EP 1 664 093 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	13.08.2008 Bulletin 2008/33

(45)	Mention of the grant of the patent:
	30.04.2008 Bulletin 2008/18

(21)	Application number: 04768394.1

(22)	Date of filing: 09.09.2004

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International Patent Classification (IPC):

C07K 11/02^(2006.01)
A61K 38/15^(2006.01)

C07K 7/64^(2006.01)

(86)	International application number:
	PCT/GB2004/003847

(87)	International publication number:
	WO 2005/023846 (17.03.2005 Gazette 2005/11)

(54)	Antitumoral compounds based on Kahalalide F Antitumorverbindungen basiert auf Kahalalide F Composes anti-tumoraux à base de Kahalalide F

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL HR LT LV MK

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Priority:

09.09.2003 GB 0321066

(43)	Date of publication of application:
	07.06.2006 Bulletin 2006/23

(60)	Divisional application:
	08100973.0 / 1918296

(73)	Proprietor: Pharma Mar, S.A.U.
	28770 Madrid (ES)

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Inventors:

ALBERICIO PALOMERA, Fernando, Univ. of Barcelona
E-08028 Barcelona (ES)
FERNANDEZ DONIS, Ariadna, Univ. of Barcelona
E-08028 Barcelona (ES)
GIRALT LLEDO, Ernest, Univ. of Barcelona
E-08028 Barcelona (ES)
GRACIA CANTADOR, Carolina, Univ. of Barcelona
E-08028 Barcelona (ES)
LOPEZ RODRIGUEZ, Pilar University of Barcelona
E-08028 Barcelona (ES)
VARON COLOMER, Sonia University of Barcelona
E-08028 Barcelona (ES)
CUEVAS MARCHANTE, Carmen
E-28770 Madrid (ES)
LOPEZ MACIA, Angel
E-28770 Madrid (ES)
FRANCESCH SOLLOSO, Andrés
E-28770 Madrid (ES)
JIMENEZ GARCIA,José-Carlos University of Barcelona
E-08028 Barcelona (ES)
ROYO EXPOSITO, Miriam University of Barcelona
E-08028 Barcelona (ES)

(74)	Representative: Ruffles, Graham Keith
	Marks & Clerk 62-68 Hills Road Cambridge CB2 1LA Cambridge CB2 1LA (GB)

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References cited: :

WO-A-01/58934
WO-A-20/04035613

WO-A-03/033012

HAMANN M T ET AL: "Kahalalides: bioactive peptides from a marine mollusk Elysia rufescens and its algal diet Bryopsis sp" JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 61, no. 19, 1996, pages 6594-6600, XP002125310 ISSN: 0022-3263 cited in the application
LÓPEZ-MACIÀ A ET AL: "Synthesis and structure determination of kahalalide F (1,2)." JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 21 NOV 2001, vol. 123, no. 46, 21 November 2001 (2001-11-21), pages 11398-11401, XP002313084 ISSN: 0002-7863


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).