(19)

(11)

EP 1 664 278 A1

(12)

(43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04768294.3 (22) Date of filing: 02.09.2004

(51) International Patent Classification (IPC):  C12N 1/21(1990.01) C07K 16/00(1995.01) C12N 15/72(1990.01) C12P 21/02(1980.01) (86) International application number: PCT/GB2004/003747 (87) International publication number: WO 2005/024000 (17.03.2005 Gazette 2005/11)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 09.09.2003 GB 0321100 (71) Applicant: Celltech R & D Limited Slough, Berkshire SL1 3WE (GB)	(72) Inventors: GLOVER, David John, Celltech R & D Limited Slough, Berkshire SL1 3WE (GB) SEHDEV, Mukesh, Celltech R & D Limited Slough, Berkshire SL1 3WE (GB) REEKS, Dominic Gambier, Celltech R & D Limited Slough, Berkshire SL1 3WE (GB) (74) Representative: Thompson, John  UCB Celltech, 208 Bath Road Slough, Berkshire SL1 3WE Slough, Berkshire SL1 3WE (GB)