(19)

(11)

EP 1 664 350 A2

(12)

(88) Date of publication A3: 22.12.2005 (43) Date of publication: 07.06.2006 Bulletin 2006/23 (21) Application number: 04789156.9 (22) Date of filing: 27.09.2004

(51) International Patent Classification (IPC):  C12Q 1/68(1980.01) C07H 21/04(1974.07) C12P 19/34(1980.01) (86) International application number: PCT/US2004/031804 (87) International publication number: WO 2005/030984 (07.04.2005 Gazette 2005/14)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 26.09.2003 US 506247 P (71) Applicant: DATASCOPE INVESTMENT CORP. Montvale, N.J. 07645 (US)	(72) Inventor: KADUSHIN, James M., Datascope Investment Corp. Montvale, NJ 07645 (US) (74) Representative: Schmidt, Karsten et al Albihns GmbH, Bayerstrasse 83 80335 München 80335 München (DE)