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(11)

EP 1 667 672 A1

(12)

(43) Date of publication: 14.06.2006 Bulletin 2006/24 (21) Application number: 04773691.3 (22) Date of filing: 01.10.2004

(51) International Patent Classification (IPC):  A61K 31/20(1985.01) A61P 25/28(2000.01) A61K 9/70(1974.07) A61P 43/00(2000.01) (86) International application number: PCT/JP2004/014893 (87) International publication number: WO 2005/032537 (14.04.2005 Gazette 2005/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 03.10.2003 US 507952 P 11.06.2004 JP 2004174577 (71) Applicant: ONO PHARMACEUTICAL CO., LTD. Osaka-shi, Osaka 541-8526 (JP)	(72) Inventors: FUNAKOSHI, Yosuke, c/o Ono Pharmaceutical Co. Ltd. Osaka-shi, Osak a 541-8526 (JP) MIZUSHIMA, Ken, c/o Ono Pharmaceutical Co., Ltd. Osaka-shi, Osaka 541-8526 (JP) TAKAKUWA, Toshio, c/o Ono Pharmaceutical Co., Ltd. Mishima-gun, OSaka 618-8585 (JP) (74) Representative: Henkel, Feiler & Hänzel  Möhlstrasse 37 D-81675 München D-81675 München (DE)