(19)

(11)

EP 1 670 473 A1

(12)

(43) Date of publication: 21.06.2006 Bulletin 2006/25 (21) Application number: 03818857.9 (22) Date of filing: 15.10.2003

(51) International Patent Classification (IPC):  A61K 31/4706(2000.01) C07D 401/12(1990.01) C07D 407/12(1990.01) C07D 405/12(1990.01) A61K 31/4709(2000.01) C07D 215/54(1985.01) C07D 417/12(1990.01) C07D 413/12(1990.01) C07D 409/12(1990.01) A61K 31/506(2000.01) (86) International application number: PCT/US2003/032612 (87) International publication number: WO 2005/034955 (21.04.2005 Gazette 2005/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 15.09.2003 US 662273 (71) Applicant: Wyeth a Corporation of the State of Delaware Madison, NJ 07940 (US)	(72) Inventors: WISSNER, Allan Ardsley, NY 10502 (US) RABINDRAN, Sridhar, Krishna Chestnut Ridge, NY 10977 (US) TSOU, Hwei-Ru New City, NY 10956 (US) (74) Representative: Mannion, Sally Kim  Wyeth Pharmaceuticals, Huntercombe Lane South, Taplow Maidenhead, Berkshire SL6 0PH Maidenhead, Berkshire SL6 0PH (GB)