(19)

(11)

EP 1 670 899 A2

(12)

(43) Date of publication: 21.06.2006 Bulletin 2006/25 (21) Application number: 04809624.2 (22) Date of filing: 26.08.2004

(51) International Patent Classification (IPC):  C12N 1/00(1980.01) (86) International application number: PCT/US2004/027792 (87) International publication number: WO 2005/035714 (21.04.2005 Gazette 2005/16)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 26.08.2003 US 498238 P (71) Applicant: Board of Regents, The University of Texas System Austin TX 78701 (US)	(72) Inventor: MOLLDREM, Jeffrey Houston, TX 77062 (US) (74) Representative: Dehmel, Albrecht  Dehmel & Bettenhausen Patentanwälte Herzogspitalstrasse 11 80331 München 80331 München (DE)