METHOD OF IN VITRO DIFFERENTIATION OF NEURAL STEM CELLS, MOTOR NEURONS AND DOPAMINE NEURONS FROM PRIMATE EMBRYONIC STEM CELLS - Patent 1670901

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EP 1 670 901 A2

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(88)	Date of publication A3:
	19.05.2005

(43)	Date of publication:
	21.06.2006 Bulletin 2006/25

(21)	Application number: 04782339.8

(22)	Date of filing: 27.08.2004

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International Patent Classification (IPC):

C12N 5/02^(1980.01)

(86)	International application number:
	PCT/US2004/027841

(87)	International publication number:
	WO 2005/021720 (10.03.2005 Gazette 2005/10)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

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Priority:

29.08.2003 US 498831 P
02.09.2003 US 499570 P

(71)	Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
	Madison, WI 53705 (US)

(72)	Inventors:
	ZHANG, Su-Chun Middleton, WI 53562 (US) THOMSON, James, A. Madison, WI 53705 (US) DUNCAN, Ian, David Madison, WI 53705 (US) LI, Xue-jun Madison, WI 53705 (US)

(74)	Representative: Duckworth, Timothy John et al
	J.A. Kemp & Co., 14 South Square, Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)

(54)	METHOD OF IN VITRO DIFFERENTIATION OF NEURAL STEM CELLS, MOTOR NEURONS AND DOPAMINE NEURONS FROM PRIMATE EMBRYONIC STEM CELLS