(19)
(11) EP 1 670 915 A2

(12)

(88) Date of publication A3:
29.12.2005

(43) Date of publication:
21.06.2006 Bulletin 2006/25

(21) Application number: 04816223.4

(22) Date of filing: 15.09.2004
(51) International Patent Classification (IPC): 
C12N 15/11(1990.01)
(86) International application number:
PCT/US2004/031012
(87) International publication number:
WO 2005/028650 (31.03.2005 Gazette 2005/13)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL HR LT LV MK

(30) Priority: 16.09.2003 US 667271
23.10.2003 US 693059
24.11.2003 US 720448
03.12.2003 US 727780
14.01.2004 US 757803
10.02.2004 US 543480 P
13.02.2004 US 780447
16.04.2004 US 826966
30.04.2004 WO PCT/US20/04013456
24.05.2004 WO PCT/US20/04016390

(71) Applicant: Sirna Therapeutics, Inc.
Boulder, CO 80301 (US)

(72) Inventors:
  • JADHAV, Vasant
    Boulder, CO 80302 (US)
  • KOSSEN, Karl
    Westminster, CO 80020 (US)
  • ZINNEN, Shawn
    Denver, CO 80027 (US)
  • VAISH, Narendra
    Denver, CO 80218 (US)
  • MCSWIGGEN, James
    Boulder, CO 80301 (US)

(74) Representative: Maschio, Antonio 
D Young & Co 120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)

   


(54) RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS (HCV) EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)