(19)

(11)

EP 1 671 116 A2

(12)

(88) Date of publication A3: 20.10.2005 (43) Date of publication: 21.06.2006 Bulletin 2006/25 (21) Application number: 04761503.4 (22) Date of filing: 06.10.2004

(51) International Patent Classification (IPC):  G01N 31/00(1968.09) A61K 31/70(1985.01) C07H 21/04(1974.07) A01N 43/00(1985.01) C07H 21/02(1974.07) C07H 21/00(1974.07) (86) International application number: PCT/BE2004/000142 (87) International publication number: WO 2005/033694 (14.04.2005 Gazette 2005/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 06.10.2003 US 508959 P (71) Applicant: UNIVERSITEIT GENT 9000 Gent (BE)	(72) Inventors: VERBRUGGEN, August B-9810 Nazareth (BE) ELEWAUT, Dirk B-9052 Gent (BE) WANG, Jun B-3000 Leuven (BE) (74) Representative: Bird, Ariane et al Bird Goën & Co Klein Dalenstraat 42A 3020 Winksele 3020 Winksele (BE)