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EP 1 673 335 A2

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(43) Date of publication: 28.06.2006 Bulletin 2006/26 (21) Application number: 05763911.4 (22) Date of filing: 28.06.2005

(51) International Patent Classification (IPC):  C07C 213/06(2006.01) C07C 213/10(2006.01) C07C 217/48(2006.01) (86) International application number: PCT/US2005/023419 (87) International publication number: WO 2006/004976 (16.02.2006 Gazette 2006/07)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 28.06.2004 US 583641 P 28.06.2004 US 583643 P 28.06.2004 US 583644 P 14.09.2004 US 606716 P 25.10.2004 US 622065 P 11.02.2005 US 652332 P 11.02.2005 US 652330 P 11.02.2005 US 652331 P 30.03.2005 US 666666 P 26.04.2005 US 675369 P 09.06.2005 US 689778 P 14.06.2005 US 690738 P (71) Applicant: Teva Pharmaceutical Fine Chemicals S.R.L. 23892 Bulciago (IT)

(72) Inventors: CASTELLI, Eugenio Lecco (IT) LO MONACO, Giuseppe Seregno (IT) MANTOVANI, Silvia 45026 Lendinara (IT) DAVERIO, Paola 20058 Villasanta (IT) RIVA, Paola 20052 Monza, Milano (IT) BIANCHI, Stefano 22100 Breccia, Como (IT) (74) Representative: Wong, Kit Yee et al D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)