(19)

(11)

EP 1 680 116 A1

(12)

(43) Date of publication: 19.07.2006 Bulletin 2006/29 (21) Application number: 04791298.5 (22) Date of filing: 22.10.2004

(51) International Patent Classification (IPC):  A61K 31/454(2000.01) A61K 31/343(2000.01) A61K 31/352(2000.01) A61K 31/16(1985.01) A61K 31/4164(2000.01) A61K 31/4965(2000.01) A61K 31/4166(2000.01) A61K 31/785(1985.01) A61K 31/5355(2000.01) A61K 31/05(1985.01) A61K 31/353(2000.01) A61K 31/165(1985.01) A61K 31/397(2000.01) A61K 31/497(2000.01) A61K 31/365(1985.01) (86) International application number: PCT/EP2004/052643 (87) International publication number: WO 2005/039579 (06.05.2005 Gazette 2005/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 24.10.2003 EP 03103962 27.10.2003 US 513996 P (71) Applicant: Solvay Pharmaceuticals GmbH 30173 Hannover (DE)	(72) Inventors: ANTEL, Jochen 31848 Bad Münder (DE) GREGORY, Peter-Colin 30559 Hannover (DE) KRAUSE, Günter 31303 Burgdorf (DE) (74) Representative: Gosmann, Martin  c/o Solvay Pharmaceuticals GmbH, PH-ZP (IPSI), Hans Böckler Allee 20 30173 Hannover 30173 Hannover (DE)