(19)

(11)

EP 1 682 484 A1

(12)

(43) Date of publication: 26.07.2006 Bulletin 2006/30 (21) Application number: 03818933.8 (22) Date of filing: 31.10.2003

(51) International Patent Classification (IPC):  C07C 217/14(2006.01) A61K 31/138(2006.01) A61K 31/435(2006.01) C07D 295/088(2006.01) A61K 31/40(2006.01) A61K 31/495(2006.01) (86) International application number: PCT/IB2003/004853 (87) International publication number: WO 2005/042465 (12.05.2005 Gazette 2005/19)

(84) Designated Contracting States: DE FR GB (71) Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH New Delhi 100 001 (IN)

(72) Inventors: CHATURVEDI, D., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) KUMAR, A., Central Drug Res. Inst 226 001 Uttar Pradesh (IN) RASTOGI, R., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) SRIVASTAVA, A., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) TEWARI, P., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) AHMAD, R., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) CHANDER, R., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) PURI, A., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) BHATIA, G., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) RIVIZ, F., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) RASTOGI, A.K., Central Drug Res. Inst 226 001 Uttar Pradesh (IN) RAY, S., Central Drug Res. Inst. 226 001 Uttar Pradesh (IN) (74) Representative: Heinze, Ekkehard et al Meissner, Bolte & Partner GbR Postfach 86 06 24 81633 München 81633 München (DE)