(19)

(11)

EP 1 687 025 A1

(12)

(43) Date of publication: 09.08.2006 Bulletin 2006/32 (21) Application number: 04790465.1 (22) Date of filing: 11.10.2004

(51) International Patent Classification (IPC):  A61K 39/39(2006.01) A61P 31/12(2006.01) A61P 31/02(2006.01) A61P 37/04(2006.01) (86) International application number: PCT/EP2004/011620 (87) International publication number: WO 2005/039634 (06.05.2005 Gazette 2005/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: HR LT LV (30) Priority: 13.10.2003 GB 0323965 (71) Applicants: Glaxosmithkline Biologicals S.A. 1330 Rixensart (BE) SMITHKLINE BEECHAM CORPORATION Philadelphia, Pennsylvania 19101 (US)	(72) Inventors: BRUCK, Claudine, Elvire, Marie King of Prussia, PA 19406 (US) GERARD, Catherine, M. G. B-1330 Rixensart (BE) JONAK , Zdenka, Ludmila King of Prussia, PA 19406 (US) (74) Representative: Lovatt, Victoria Jayne  GlaxoSmithKline Plc Corporate Intellectual Property Department 980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)