(19)

(11)

EP 1 687 286 A1

(12)

(43) Date of publication: 09.08.2006 Bulletin 2006/32 (21) Application number: 04798628.6 (22) Date of filing: 22.11.2004

(51) International Patent Classification (IPC):  C07D 279/18(2006.01) A61K 31/5415(2006.01) C07D 401/04(2006.01) (86) International application number: PCT/GB2004/004918 (87) International publication number: WO 2005/054217 (16.06.2005 Gazette 2005/24)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 28.11.2003 GB 0327672 23.12.2003 GB 0329809 (71) Applicant: Photopharmica Limited Leeds LS2 9DF (GB)

(72) Inventors: BROWN, Stanley Beames Burley-in-Wharfedale, West Yorkshire (GB) O'GRADY, Cassandra Claire Burley, Leeds LS4 2PP (GB) GRIFFITHS, John Gosforth, Leeds LS25 1JX (GB) MELLISH, Kirste, Joanne Leeds LS27 8QN (GB) TUNSTALL, Richard George Burley in Wharfedale, Ilkley LS29 7HY (GB) ROBERTS, David John Howard Leeds LS8 2JW (GB) VERNON, David Ian Leeds LS7 3NX (GB) (74) Representative: Giles, David Eric  Photopharmica Limited 103 Clarendon Road Leeds West Yorkshire LS2 9DF Leeds West Yorkshire LS2 9DF (GB)