(19)

(11)

EP 1 687 446 A2

(12)

(88) Date of publication A3: 18.05.2006 (43) Date of publication: 09.08.2006 Bulletin 2006/32 (21) Application number: 04795442.5 (22) Date of filing: 18.10.2004

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) C07H 21/02(2006.01) C12P 19/34(2006.01) (86) International application number: PCT/US2004/034279 (87) International publication number: WO 2005/038041 (28.04.2005 Gazette 2005/17)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 16.10.2003 US 511955 P 02.03.2004 US 549527 P 09.03.2004 US 551669 P (71) Applicant: THIRD WAVE TECHNOLOGIES, INC. Madison, WI 53719-1256 (US)	(72) Inventors: LYAMICHEV, Victor Madison, WI 53711 (US) LUKOWIAK, Andrew, A. Stoughton, WI 53589 (US) JARVIS, Nancy Madison, WI 53704 (US) ROEVEN, Robert Stoughton, WI 53589 (US) HALL, Jeff, G. Madison, WI 53719 (US) ALLAWI, Hatim, T. Madison, WI 53717 (US) (74) Representative: Glawe, Delfs, Moll  Patent- und Rechtsanwälte, Rothenbaumchaussee 58 20148 Hamburg 20148 Hamburg (DE)