| (19) |
 |
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(11) |
EP 1 690 939 A3 |
| (12) |
EUROPEAN PATENT APPLICATION |
| (88) |
Date of publication A3: |
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30.08.2006 Bulletin 2006/35 |
| (43) |
Date of publication A2: |
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16.08.2006 Bulletin 2006/33 |
| (22) |
Date of filing: 11.03.1999 |
|
| (51) |
International Patent Classification (IPC):
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| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
| (30) |
Priority: |
12.03.1998 JP 6024598
03.02.1999 JP 2677499
|
| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
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99939146.9 / 1067183 |
| (71) |
Applicant: Astellas Pharma Inc. |
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Tokyo 103-8411 (JP) |
|
| (72) |
Inventors: |
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- Sugimoto, Toru
Tsukuba-shi,
Ibaraki 3005-8585 (JP)
- Kamohara, Masazumi
Tsukuba-shi,
Ibaraki 3005-8585 (JP)
- Kamohara, Masazumi
Tsukuba-shi,
Ibaraki 3005-8585 (JP)
- Matsumoto, Mitsuyuki
Tsukuba-shi,
Ibaraki 3005-8585 (JP)
- Kobayashi, Masato
3-chome,
Itabashi-ku,
Tokyo 174-8612 (JP)
|
| (74) |
Representative: HOFFMANN EITLE |
|
Patent- und Rechtsanwälte
Arabellastrasse 4
81925 München
81925 München (DE) |
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| |
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| (54) |
Novel G protein-coupled receptor proteins |
(57) This invention belongs to the genetic engineering field, and provides the novel G
protein-coupled receptor family protein SREB3 expressed in the central nervous system,
genes coding for this protein, screening methods using this protein and so on.
As one of the methods for obtaining the G protein-coupled receptor proteins of the
present invention, RT-PCR is carried out using mRNA extracted from human or rat brain
tissue or brain-derived cells as the template and using two primers interposing the
entire portion or a part of the G protein-coupled receptor protein translation region,
thereby obtaining cDNA corresponding to the G protein-coupled receptor protein or
a part thereof, and the cDNA is integrated into an appropriate expression vector and
expressed in a host cell.