(19)
(11) EP 1 694 331 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
24.02.2010 Bulletin 2010/08

(45) Mention of the grant of the patent:
11.11.2009 Bulletin 2009/46

(21) Application number: 04813574.3

(22) Date of filing: 09.12.2004
(51) International Patent Classification (IPC): 
A61K 31/496(2006.01)
A61P 37/06(2006.01)
 A61P 35/00(2006.01)
(86) International application number:
PCT/US2004/041265
(87) International publication number:
WO 2005/056014 (23.06.2005 Gazette 2005/25)

(54)

METHODS FOR SUPPRESSING AN IMMUNE RESPONSE OR TREATING A PROLIFERATING DISORDER

VERFAHREN ZUR UNTERDRÜCKUNG EINER IMMUNANTWORT ODER ZUR BEHANDLUNG VON PROLIFERATIVEN ERKRANKUNGEN

PROCEDES PERMETTANT DE SUPPRIMER UNE REPONSE IMMUNITAIRE OU DE TRAITER UN TROUBLE PROLIFERATIF

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

(30) Priority: 09.12.2003 US 528340 P

(43) Date of publication of application:
30.08.2006 Bulletin 2006/35

(73) Proprietor: THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
Rockville, MD 20852-3804 (US)

(72) Inventors:
  • MOSS, Joel
    Bethesda, MD 20814 (US)
  • KRISTOF, Arnold
    Montreal, Quebec H4B 2S5 (CA)

(74) Representative: Laufer, Gabriele et al
Witte, Weller & Partner Patentanwälte Postfach 10 54 62
70047 Stuttgart
70047 Stuttgart (DE)


(56) References cited: : 
   
  • SHEGOGUE DANIEL A ET AL: "Collagen mRNA stability is regulated by mTOR via a PI3-Kinase independent pathway" MOLECULAR BIOLOGY OF THE CELL, vol. 12, no. Supplement, November 2001 (2001-11), page 325a, XP009045962 & 41ST ANNUAL MEETING OF THE AMERICAN SOCIETY FOR CELL BIOLOGY; WASHINGTON DC, USA; DECEMBER 08-12, 2001 ISSN: 1059-1524
  • EL-KHOLY WASIM ET AL: "The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks KV currents via a direct mechanism." FASEB JOURNAL, vol. 17, no. 6, April 2003 (2003-04), pages 720-722 URL, XP002323402 ISSN: 0892-6638
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).