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EP 1 697 351 A1

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(43) Date of publication: 06.09.2006 Bulletin 2006/36 (21) Application number: 04814183.2 (22) Date of filing: 14.12.2004

(51) International Patent Classification (IPC):  C07D 405/14(2006.01) C07D 401/14(2006.01) A61K 31/506(2006.01) A61P 11/06(2006.01) C07D 409/14(2006.01) C07D 417/14(2006.01) A61P 37/00(2006.01) A61P 9/00(2006.01) (86) International application number: PCT/US2004/041970 (87) International publication number: WO 2005/058883 (30.06.2005 Gazette 2005/26)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 15.12.2003 ES 200302951 05.10.2004 WO PCT/EP2004/011086 (71) Applicant: Almirall Prodesfarma AG 6340 Baar (CH)

(72) Inventors: CRESPO CRESPO, Maria, Isabel E-08036 Barcelona (ES) PRAT, QUINONES, Maria E-08003 Barcelona (ES) GUAL ROIG, Silvia E-08349 Cabrera del Mar (ES) CASTRO PALOMINO LARIA, Julio, Cesar E-08330 Premia del Mar (ES) SLEE, Deborah, H. Cardiff by the Sea, CA 92007 (US) (74) Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät  Maximilianstrasse 58 80538 München 80538 München (DE)