(19)

(11)

EP 1 706 118 A1

(12)

(43) Date of publication: 04.10.2006 Bulletin 2006/40 (21) Application number: 05700675.1 (22) Date of filing: 04.01.2005

(51) International Patent Classification (IPC):  A61K 31/455(2006.01) A61P 11/06(2006.01) A61K 31/46(2006.01) (86) International application number: PCT/EP2005/000010 (87) International publication number: WO 2005/067929 (28.07.2005 Gazette 2005/30)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 09.01.2004 EP 04000327 (71) Applicants: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE) AT BE BG CH CY CZ DK EE ES FI GB HU IS LI  Boehringer Ingelheim Pharma GmbH & Co.KG 55216 Ingelheim am Rhein (DE) DE	(72) Inventors: MEADE, Christopher, John, Montague 88437 Maselheim (DE) PAIRET, Michel 88400 Biberach (DE) PIEPER, Michael, P. 88400 Biberach (DE) (74) Representative: Hammann, Heinz et al Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)