(19)

(11)

EP 1 709 016 A1

(12)

(43) Date of publication: 11.10.2006 Bulletin 2006/41 (21) Application number: 05704294.7 (22) Date of filing: 25.01.2005

(51) International Patent Classification (IPC):  C07D 263/58(2006.01) (86) International application number: PCT/JP2005/001297 (87) International publication number: WO 2005/070907 (04.08.2005 Gazette 2005/31)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 26.01.2004 US 763241 (71) Applicant: Kowa Company. Ltd. Nagoya-shi Aichi-ken, 460-8625 (JP)	(72) Inventors: SHIBUYA, Kimiyuki Tokorozawa-shi, Saitama 3591142 (JP) MIURA, Toru Higashimurayama-shi, Tokyo 1890022 (JP) (74) Representative: Hartz, Nikolai  Wächtershauser & Hartz Weinstrasse 8 80333 München 80333 München (DE)