(19)
(11) EP 1 711 487 A1

(12)

(43) Date of publication:
18.10.2006 Bulletin 2006/42

(21) Application number: 05712910.8

(22) Date of filing: 04.02.2005
(51) International Patent Classification (IPC): 
C07D 403/06(2006.01)
C07D 405/14(2006.01)
C07D 487/04(2006.01)
A61P 31/00(2006.01)
 C07D 403/14(2006.01)
C07D 407/14(2006.01)
A61K 31/496(2006.01)
A61P 35/00(2006.01)
(86) International application number:
PCT/US2005/003636
(87) International publication number:
WO 2005/077940 (25.08.2005 Gazette 2005/34)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

(30) Priority: 04.02.2004 US 542073 P
01.11.2004 US 624262 P

(71) Applicant: Nereus Pharmaceuticals, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • PALLADINO, Michael, A.
    Olivenhain, CA 92024 (US)
  • LLOYD, George, Kenneth
    Poway, CA 92064 (US)
  • HAYASHI, Yoshio
    Ritto, Shiga 520-3031 (JP)
  • NICHOLSON, Benjamin
    San Diego, CA 92103 (US)

(74) Representative: Neuefeind, Regina 
Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3
80335 München
80335 München (DE)

   


(54) DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF AND THE SYNTHESIS OF DEHYDROPHENYLAHISTINS AND ANALOGS THEREOF