(19)

(11)

EP 1 711 528 A2

(12)

(88) Date of publication A3: 13.10.2005 (43) Date of publication: 18.10.2006 Bulletin 2006/42 (21) Application number: 04815598.0 (22) Date of filing: 23.12.2004

(51) International Patent Classification (IPC):  C07K 16/00(2006.01) G01N 33/53(2006.01) A61K 39/395(2006.01) (86) International application number: PCT/US2004/043541 (87) International publication number: WO 2005/062972 (14.07.2005 Gazette 2005/28)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 23.12.2003 US 532130 P (71) Applicant: Tanox, Inc. Houston, TX 77025 (US)	(72) Inventors: FUNG, Sek, Chung Houston, TX 75025 (US) MOYLE, Matthew Houston, TX 77027 (US) (74) Representative: van Kooij, Adriaan et al Arnold & Siedsma Sweelickplein 1 2517 GK The Hague 2517 GK The Hague (NL)