(19)

(11)

EP 1 713 820 A1

(12)

(43) Date of publication: 25.10.2006 Bulletin 2006/43 (21) Application number: 05704873.8 (22) Date of filing: 18.01.2005

(51) International Patent Classification (IPC):  C07J 73/00(2006.01) A61P 5/32(2006.01) A61K 31/56(2006.01) (86) International application number: PCT/US2005/000019 (87) International publication number: WO 2005/073244 (11.08.2005 Gazette 2005/32)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 22.01.2004 US 538302 P (71) Applicant: ELI LILLY AND COMPANY Indianapolis, Indiana 46285 (US)	(72) Inventors: DODGE, Jeffrey, Alan Indianapolis, Indiana 46256 (US) HOPKINS, Randall, Bruce Indianapolis, Indiana 46219 (US) WALLACE, Owen, Brendan Zionsville, Indiana 46077 (US) (74) Representative: Burnside, Ivan John  Eli Lilly and Company Limited European Patent Operations Lilly Research Centre Erl Wood Manor, Sunnighill Road Windlesham, Surrey GU20 6PH Windlesham, Surrey GU20 6PH (GB)