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(11)

EP 1 718 302 A1

(12)

(43) Date of publication: 08.11.2006 Bulletin 2006/45 (21) Application number: 05712759.9 (22) Date of filing: 28.01.2005

(51) International Patent Classification (IPC):  A61K 31/44(2006.01) (86) International application number: PCT/US2005/003427 (87) International publication number: WO 2005/074926 (18.08.2005 Gazette 2005/33)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 30.01.2004 GB 0402100 (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: OTTLECZ, Anna CH-4055 Basel (CH) GIGER, Rudolf, Karl, Andreas CH-4132 Muttenz (CH) ALVAREZ, Carlos CH-4125 Riehen (CH) (74) Representative: Waldren, Robin Michael et al Lloyd Wise, McNeight & Lawrence Commonwealth House 1-19 New Oxford Street London WC1A 1LW London WC1A 1LW (GB)