(19)
(11) EP 1 725 250 A2

(12)

(88) Date of publication A3:
08.09.2006

(43) Date of publication:
29.11.2006 Bulletin 2006/48

(21) Application number: 05709106.8

(22) Date of filing: 17.02.2005
(51) International Patent Classification (IPC): 
A61K 38/14(2006.01)
 C07K 9/00(2006.01)
(86) International application number:
PCT/IL2005/000204
(87) International publication number:
WO 2005/076744 (25.08.2005 Gazette 2005/34)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 18.02.2004 US 545173 P

(71) Applicants:
  • FRUTAROM LTD.
    26110 Haifa (IL)
  • Yissum Research Development Company of the Hebrew University of Jerusalem
    91390 Jerusalem (IL)

(72) Inventors:
  • KATZHENDLER, Jehoshua
    92583 Jerusalem (IL)
  • KLAUZNER, Yakir
    93714 Jerusalem (IL)
  • BEYLIS, Irena
    67655 Tel Aviv (IL)
  • MIZHIRITSKII, Michael
    76209 Rehovot (IL)
  • SHPERNAT, Yaacov
    55454 Kiriat-Ono (IL)
  • ASHKENAZI, Boris
    Rehovot 76549 (IL)
  • FRIDLAND, Dmitri
    77497 Ashdod (IL)

(74) Representative: Becker Kurig Straus 
Patentanwälte Bavariastrasse 7
80336 München
80336 München (DE)

   


(54) METHOD FOR THE PREPARATION OF PEPTIDE-OLIGONUCLEOTIDE CONJUGATES