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(11)

EP 1 727 570 A1

(12)

(43) Date of publication: 06.12.2006 Bulletin 2006/49 (21) Application number: 05723806.5 (22) Date of filing: 22.02.2005

(51) International Patent Classification (IPC):  A61L 27/12(2006.01) A61F 2/28(2006.01) A61L 27/56(2006.01) (86) International application number: PCT/US2005/006100 (87) International publication number: WO 2005/079880 (01.09.2005 Gazette 2005/35)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 19.02.2004 US 780728 25.05.2004 US 852167 (71) Applicant: Calcitec, Inc. Austin TX 78735 (US)	(72) Inventors: LIN, Jiin-Huey, Chern Winnetka, Illinois 60093 (US) JU, Chien-Ping Carbondale, Illinois 62901 (US) TSAI, Chih-Hung Bei Chiu Taichung (TW) TIEN, Yin-Chun Kaohsiung (TW) NING, Chao-Chin Kaohsiung (TW) CHAO, Chung-Po Taoyuan County (TW) (74) Representative: Bartle, Robin Jonathan  W.P. Thompson & Co. Coopers Building Church Street Liverpool L1 3AB Liverpool L1 3AB (GB)