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(11)

EP 1 727 785 A1

(12)

(43) Date of publication: 06.12.2006 Bulletin 2006/49 (21) Application number: 05706813.2 (22) Date of filing: 08.03.2005

(51) International Patent Classification (IPC):  C07C 229/14(2006.01) C07D 333/20(2006.01) A61P 25/00(2006.01) C07D 295/12(2006.01) A61K 31/195(2006.01) (86) International application number: PCT/DK2005/000152 (87) International publication number: WO 2005/087708 (22.09.2005 Gazette 2005/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 12.03.2004 US 552867 P 12.03.2004 DK 200400413 (71) Applicant: H.Lundbeck A/S 2500 Valby-Copenhagen (DK)	(72) Inventors: SMITH, Garrick, Paul DK-2500 Valby (DK) ANDERSEN, Kim Ridgewood, NJ 07450 (US) WREN, Stephen, P. Rickmansworth Hertfordshire WD3 8RW (GB) HARRIS, Neil Dunmow Essex CM6 1ZA (GB) BRANDT, Guillaume Harlow Essex CM20 1JQ (GB) (74) Representative: Conrad, Lars Sparre et al H. Lundbeck A/S Ottiliavej 9 DK-2500 Valby DK-2500 Valby (DK)