(19)
(11) EP 1 727 809 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
29.10.2008 Bulletin 2008/44

(45) Mention of the grant of the patent:
11.06.2008 Bulletin 2008/24

(21) Application number: 05706819.9

(22) Date of filing: 09.03.2005
(51) International Patent Classification (IPC): 
C07D 295/12(2006.01)
C07D 279/12(2006.01)
A61K 31/4406(2006.01)
A61K 31/5355(2006.01)
C07D 265/06(2006.01)
C07D 417/04(2006.01)
A61K 31/541(2006.01)
A61P 25/22(2006.01)
(86) International application number:
PCT/DK2005/000159
(87) International publication number:
WO 2005/087754 (22.09.2005 Gazette 2005/38)

(54)

SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES

SUBSTITUIERTE MORPHOLIN- UND THIOMORPHOLINDERIVATE

DERIVÉS DE MORPHOLINE ET DE THIOMORPHOLINE SUBSTITUÉS


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 12.03.2004 DK 200400412
12.03.2004 US 552574 P

(43) Date of publication of application:
06.12.2006 Bulletin 2006/49

(60) Divisional application:
08007169.9 / 1947093

(73) Proprietor: H. Lundbeck A/S
2500 Valby-Copenhagen (DK)

(72) Inventors:
  • WENZEL TORNØE, Christian
    DK-2300 Copenhagen S (DK)
  • ROTTLÄNDER, Mario
    DK-2670 Greve (DK)
  • KHANZHIN, Nikolay
    DK-3050 Humlebaek (DK)
  • RITZÉN, Andreas
    DK-2720 Vanløse (DK)
  • WATSON, William Patrick
    DK-2720 Vanløse (DK)


(56) References cited: : 
WO-A-02/49628
US-A1- 2001 049 444
WO-A-02/066036
   
  • MAIN M J ET AL: "MODULATION OF KCNQ2/3 POTASSIUM CHANNELS BY THE NOVEL ANTICONVULSANT RETIGABINE" MOLECULAR PHARMACOLOGY, BALTIMORE, MD, US, vol. 58, no. 2, August 2000 (2000-08), pages 253-262, XP000972245 ISSN: 0026-895X
  • DATABASE BEILSTEIN BEILSTEIN CROSSFIRE INSTITUT ZUR FOERDERUNG DER CHEMISCHEN WISSENSCHAFTEN, DE; BRN 6233316 1993, XP002330358 & VERMA M AL: ARCH PHARM (WEINHEIM W GER), vol. 315, no. 7, 1982, pages 358-363,
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).