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EP 1 727 831 A1

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(43) Date of publication: 06.12.2006 Bulletin 2006/49 (21) Application number: 05721047.8 (22) Date of filing: 11.03.2005

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) C12Q 1/68(2006.01) C12N 15/11(2006.01) A61K 38/17(2006.01) G01N 33/574(2006.01) C12N 15/63(2006.01) C07K 16/18(2006.01) C12N 5/10(2006.01) (86) International application number: PCT/JP2005/004860 (87) International publication number: WO 2005/090398 (29.09.2005 Gazette 2005/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 23.03.2004 US 555810 P (71) Applicant: Oncotherapy Science, Inc. Kawasaki-shi, Kanagawa 213-0012 (JP)	(72) Inventors: NAKAMURA, Yusuke 108-8639 (JP) NAKAGAWA, Hidewaki 108-8639 (JP) NAKATSURU, Shuichi Kawasaki-shi, Kanagawa 213-0012 (JP) (74) Representative: Vossius & Partner  Siebertstrasse 4 81675 München 81675 München (DE)