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(11)

EP 1 729 570 A1

(12)

(43) Date of publication: 13.12.2006 Bulletin 2006/50 (21) Application number: 05731819.8 (22) Date of filing: 30.03.2005

(51) International Patent Classification (IPC):  A01K 67/027(2006.01) G01N 33/50(2006.01) C12N 15/85(2006.01) C07K 14/705(2006.01) A61K 38/17(2006.01) C12N 5/10(2006.01) (86) International application number: PCT/GB2005/001151 (87) International publication number: WO 2005/094569 (13.10.2005 Gazette 2005/41)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 30.03.2004 GB 0407175 08.04.2004 US 561123 P (71) Applicant: Paradigm Therapeutics Ltd. 418 Cambridge Science Park Milton Road Cambridge CB4 0PA (GB)	(72) Inventors: BRICE, Nicola, Cambridge CB4 0PA (GB) DIXON, John Cambridge CB4 0PA (GB) MESSAGER, Sophie Cambridge CB4 0PA (GB) ZAHN, Dirk Cambridge CB4 0PA (GB) (74) Representative: Khoo, Chong-Yee  D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)