(19)

(11)

EP 1 729 740 A2

(12)

(88) Date of publication A3: 05.01.2006 (43) Date of publication: 13.12.2006 Bulletin 2006/50 (21) Application number: 05733181.1 (22) Date of filing: 01.04.2005

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61K 9/48(2006.01) A61K 9/22(2006.01) A61K 9/52(2006.01) (86) International application number: PCT/US2005/011032 (87) International publication number: WO 2005/097079 (20.10.2005 Gazette 2005/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 02.04.2004 US 815930 02.04.2004 US 815926 02.04.2004 US 815924 02.04.2004 US 815929 (71) Applicant: Impax Laboratories, Inc. Haywood, CA 94544 (US)

(72) Inventors: HAN, Chien-Hsuan Sunnyvale, California 94087 (US) HSU, Ann Los Altos Hills, California 94022 (US) HSU, Larry Los Altos Hills, California 94022 (US) HSIAO, Charles Pleasanton, California 94566 (US) TENG, Ching-Ling Diana Fremont, California 94536 (US) (74) Representative: Baldock, Sharon Claire  Boult Wade Tennant Verulam Gardens 70 Gray's Inn Road London WC1X 8BT London WC1X 8BT (GB)