(19)

(11)

EP 1 735 626 A2

(12)

(88) Date of publication A3: 12.01.2006 (43) Date of publication: 27.12.2006 Bulletin 2006/52 (21) Application number: 05733475.7 (22) Date of filing: 15.04.2005

(51) International Patent Classification (IPC):  G01N 33/68(2006.01) C12N 5/10(2006.01) A01K 67/027(2006.01) (86) International application number: PCT/EP2005/051677 (87) International publication number: WO 2005/101014 (27.10.2005 Gazette 2005/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 16.04.2004 US 562609 P (71) Applicant: EVOTEC Neurosciences GmbH 22525 Hamburg (DE)	(72) Inventors: POHLNER, Johannes 22175 Hamburg (DE) VON DER KAMMER, Heinz 22607 Hamburg (DE) HANES, Jozef 84107 Breatislava IV (SK) (74) Representative: von Kreisler Selting Werner  Patentanwälte P.O. Box 10 22 41 50462 Köln 50462 Köln (DE)