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(11)

EP 1 737 379 A2

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(88) Date of publication A3: 14.09.2006 (43) Date of publication: 03.01.2007 Bulletin 2007/01 (21) Application number: 05767563.9 (22) Date of filing: 04.04.2005

(51) International Patent Classification (IPC):  A61F 2/00(2006.01) A61F 2/04(2006.01) A61F 2/82(2006.01) A61F 2/02(2006.01) A61F 2/06(2006.01) A61K 9/00(2006.01) (86) International application number: PCT/US2005/011231 (87) International publication number: WO 2005/097186 (20.10.2005 Gazette 2005/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR LV MK YU (30) Priority: 05.04.2004 US 559937 P (71) Applicant: Medivas, LLC San Diego, CA 92121 (US)	(72) Inventors: CARPENTER, Kenneth, W. San Diego, CA 92103 (US) TURNELL, William, G. San Diego, CA 92014 (US) DEFIFE, Kristen, M. San Diego, California 92120 (US) GRAKO, Kathryn, A. San Diego, CA 92121 (US) (74) Representative: Lee, Nicholas John et al Kilburn & Strode, 20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)