(19)

(11)

EP 1 737 452 A1

(12)

(43) Date of publication: 03.01.2007 Bulletin 2007/01 (21) Application number: 05730890.0 (22) Date of filing: 06.04.2005

(51) International Patent Classification (IPC):  A61K 31/4402(2006.01) A61P 35/00(2006.01) A61K 39/395(2006.01) A61P 17/06(2006.01) (86) International application number: PCT/SE2005/000506 (87) International publication number: WO 2005/097121 (20.10.2005 Gazette 2005/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 06.04.2004 US 521346 P (71) Applicant: Angiogenetics Sweden AB 405 30 Gothenburg (SE)	(72) Inventors: AUGUSTIN, Helmut Tumor Biology Center Freiburg 79106 Freiburg (DE) HELLSTRÖM, Mats c/o AngioGenetics Sweden AB S-405 30 Göteborg (SE) (74) Representative: Fagerlin, Heléne  Albihns Stockholm AB, Box 5581 114 85 Stockholm 114 85 Stockholm (SE)