(19)
(11) EP 1 737 483 A2

(12)

(43) Date of publication:
03.01.2007 Bulletin 2007/01

(21) Application number: 05779405.9

(22) Date of filing: 23.04.2005
(51) International Patent Classification (IPC): 
A61K 38/17(2006.01)
C07K 14/705(2006.01)
(86) International application number:
PCT/US2005/014122
(87) International publication number:
WO 2005/117940 (15.12.2005 Gazette 2005/50)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR LV MK YU

(30) Priority: 23.04.2004 US 565283 P

(71) Applicant: University of Pittsburgh of the Commonwealth System of Higher Education
Pittsburgh, PA 15260 (US)

(72) Inventors:
  • ZARNEGAR, Abdolreza
    Gibsonia, Pennsylvania 15044 (US)
  • DEFRANCES, Marie C.
    Gibsonia, Pennsylvania 15044 (US)
  • ZOU, Chunbin
    Pittsburgh, Pennsylvania 15261 (US)

(74) Representative: Hoeger, Stellrecht & Partner Patentanwälte 
Uhlandstrasse 14 c
70182 Stuttgart
70182 Stuttgart (DE)

   


(54) CELL DEATH MODULATION VIA ANTAGONISTS OF FASL AND FAS ACTIVATION