REGIOSPECIFIC SYNTHESIS OF RAPAMYCIN 42-ESTER DERIVATIVES - Patent 1737869

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EP 1 737 869 A1

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(43)	Date of publication:
	03.01.2007 Bulletin 2007/01

(21)	Application number: 05733853.5

(22)	Date of filing: 12.04.2005

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International Patent Classification (IPC):

C07D 498/18^(2006.01)
C12P 17/18^(2006.01)

A61K 47/48^(2006.01)

(86)	International application number:
	PCT/US2005/012266

(87)	International publication number:
	WO 2005/105811 (10.11.2005 Gazette 2005/45)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	LV

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Priority:

14.04.2004 US 561926 P

(71)	Applicant: Wyeth
	Madison, NJ 07940 (US)

(72)	Inventors:
	GU, Jianxin River Edge, NJ 07661 (US) CAI, Ping New City, NY 10956 (US) RUPPEN, Mark, E. Garnerville, NY 10923 (US)

(74)	Representative: Wileman, David Francis
	Wyeth Pharmaceuticals, Patent Department, Huntercombe Lane South, Taplow, Maidenhead, Berkshire SL6 OPH Berkshire SL6 OPH (GB)

(54)	REGIOSPECIFIC SYNTHESIS OF RAPAMYCIN 42-ESTER DERIVATIVES