(19)

(11)

EP 1 740 206 A2

(12)

(88) Date of publication A3: 16.03.2006 (43) Date of publication: 10.01.2007 Bulletin 2007/02 (21) Application number: 05732793.4 (22) Date of filing: 08.04.2005

(51) International Patent Classification (IPC):  A61K 39/085(2006.01) A61P 31/04(2006.01) (86) International application number: PCT/GB2005/001384 (87) International publication number: WO 2005/105845 (10.11.2005 Gazette 2005/45)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 29.04.2004 GB 0409559 (71) Applicant: THE UNIVERSITY OF SHEFFIELD Fifth Court Western Bank, Sheffield S10 2TE (GB)	(72) Inventor: FOSTER, Simon J. Sheffield S10 2TN (GB) (74) Representative: Boakes, Jason Carrington  Harrison Goddard Foote 31 St Saviourgate York YO1 8NQ York YO1 8NQ (GB)