SUBSTITUTED PHENOXY- AND PHENYLTHIO-DERIVATIVES FOR TREATING PROLIFERATIVE DISORDERS

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EP 1 740 530 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	01.03.2017 Bulletin 2017/09

(45)	Mention of the grant of the patent:
	28.09.2016 Bulletin 2016/39

(21)	Application number: 05736001.8

(22)	Date of filing: 15.03.2005

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International Patent Classification (IPC):

C07C 235/38^(2006.01)
C07C 311/27^(2006.01)
C07C 317/28^(2006.01)
C07C 323/49^(2006.01)
C07D 213/02^(2006.01)
C07D 295/15^(2006.01)
C07F 7/18^(2006.01)

C07C 271/44^(2006.01)
C07C 317/18^(2006.01)
C07C 323/41^(2006.01)
C07C 323/65^(2006.01)
C07D 295/088^(2006.01)
C07D 295/155^(2006.01)

(86)	International application number:
	PCT/US2005/008429

(87)	International publication number:
	WO 2005/089269 (29.09.2005 Gazette 2005/39)

(54)	SUBSTITUTED PHENOXY- AND PHENYLTHIO-DERIVATIVES FOR TREATING PROLIFERATIVE DISORDERS SUBSTITUIERTE PHENOXY- UND PHENYLTHIODERIVATE ZUR BEHANDLUNG VON PROLIFERATIVEN ERKRANKUNGEN DERIVES PHENOXY- ET PHENYLTHIO-SUBSTITUES POUR TRAITER DES TROUBLES PROLIFERATIFS

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR LV MK YU

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Priority:

16.03.2004 US 554008 P

(43)	Date of publication of application:
	10.01.2007 Bulletin 2007/02

(60)	Divisional application:
	16190952.8

(73)	Proprietors:
	Temple University - Of The Commonwealth System of Higher Education Philadelphia, PA 19122 (US) Onconova Therapeutics, Inc. Newtown, PA 18940 (US)

(72)	Inventors:
	REDDY, E., Premkumar Villanova, PA 19085 (US) REDDY, M., V., Ramana Upper Darby, PA 19082-5429 (US) BELL, Stanley, C. Narberth, PA 19072 (US)

(74)	Representative: Main, Malcolm Charles
	Murgitroyd & Company Scotland House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)

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References cited: :

WO-A-2004/037751
WO-A-2006/091870
WO-A2-02/30894
US-A- 3 865 867
US-A- 6 117 364

WO-A-2005/046599
WO-A1-01/78712
WO-A2-02/067865
US-A- 3 975 435
US-A1- 2003 162 789

WALCHSHOFER N ET AL: "ANTHELMINTIC ACTIVITY OF SOME 3-SUBSTITUTED PHENYL-1-ALKYL OR PHENYL PROPENONES AND PROPENAMIDES", ARZNEIMITTEL FORSCHUNG. DRUG RESEARCH, ECV EDITIO CANTOR VERLAG, AULENDORF, DE, vol. 41, no. 10, 1 January 1991 (1991-01-01), pages 1068-1071, XP001063981, ISSN: 0004-4172
DATABASE CA [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US TREBST, ACHIM ET AL: 'Inhibition of photosynthetic reactions by herbicides of the biscarbamate type' Retrieved from STN Database accession no. 1968:113544 & TREBST, ACHIM ET AL: "Inhibition of photosynthetic reactions by herbicides of the biscarbamate type", ZEITSCHRIFT FUER NATURFORSCHUNG, TEIL B: ANORGANISCHE CHEMIE, ORGANISCHE CHEMIE, BIOCHEMIE, BIOPHYSIK, BIOLOGIE , 23(3), 342-8 CODEN: ZENBAX; ISSN: 0044-3174, 1968,
FLEISHER DAVID ET AL: "IMPROVED ORAL DRUG DELIVERY: SOLUBILITY LIMITATIONS OVERCOME BY THE USE OF PRODRUGS", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER BV, AMSTERDAM, NL, vol. 19, 1 January 1996 (1996-01-01), pages 115-130, XP002478093, ISSN: 0169-409X, DOI: 10.1016/0169-409X(95)00103-E

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