(19)

(11)

EP 1 740 582 A1

(12)

(43) Date of publication: 10.01.2007 Bulletin 2007/02 (21) Application number: 05734941.7 (22) Date of filing: 20.04.2005

(51) International Patent Classification (IPC):  C07D 417/04(2006.01) A61P 31/14(2006.01) A61K 31/427(2006.01) C07D 417/14(2006.01) (86) International application number: PCT/EP2005/004270 (87) International publication number: WO 2005/103045 (03.11.2005 Gazette 2005/44)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR Designated Extension States: HR LV (30) Priority: 22.04.2004 GB 0408995 (71) Applicant: GLAXO GROUP LIMITED Greenford, Middlesex UB6 ONN (GB)	(72) Inventors: HAIGH, David, GlaxoSmithKline Stevenage, Hertfordshire SG1 2NY (GB) SLATER, Martin John, GlaxoSmithKline Stevenage, Hertfordshire SG1 2NY (GB) (74) Representative: McKinnell, Denise  GlaxoSmithKline Corporate Intellectual Property (CN9.25.1) 980 Great West Road Brentford, Middlesex TW8 9GS Brentford, Middlesex TW8 9GS (GB)