(19)
(11) EP 1 740 600 A1

(12)

(43) Date of publication:
10.01.2007 Bulletin 2007/02

(21) Application number: 04749433.1

(22) Date of filing: 13.04.2004
(51) International Patent Classification (IPC): 
C07H 21/04(2006.01)
C07K 5/00(2006.01)
(86) International application number:
PCT/US2004/009127
(87) International publication number:
WO 2005/111058 (24.11.2005 Gazette 2005/47)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

(71) Applicant: Medtronic Sofamor Danek, Inc.
Memphis, TN 38132 (US)

(72) Inventors:
  • TITUS, Frances
    Atlanta, Georgia 30306 (US)
  • MARX, Jeffrey
    Germantown, Tennessee 38139 (US)
  • DRAPEAU, Susan
    Cordova, Tennessee 38018 (US)
  • BODEN, Scott
    Atlanta, Georgia 30345 (US)
  • YOON, Sangwook
    Atlanta, Georgia 30345 (US)

(74) Representative: Hughes, Andrea Michelle 
Frank B. Dehn & Co. St Bride's House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) INTRACELLULAR DELIVERY OF OSTEOINDUCTIVE PROTEINS AND PEPTIDES