(19)

(11)

EP 1 740 601 A2

(12)

(88) Date of publication A3: 04.05.2006 (43) Date of publication: 10.01.2007 Bulletin 2007/02 (21) Application number: 05777465.5 (22) Date of filing: 21.04.2005

(51) International Patent Classification (IPC):  C07K 7/06(2006.01) (86) International application number: PCT/US2005/013411 (87) International publication number: WO 2005/108416 (17.11.2005 Gazette 2005/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) Priority: 21.04.2004 US 564313 P (71) Applicants: The University of Chicago Chicago, Illinois 60637 (US) University College Cardiff Consultants Ltd. King Edward VII Avenue Cardiff CF1 3XF (GB) McMASTER UNIVERSITY Hamilton, Ontario L8S 4L8 (CA)	(72) Inventors: TURNER, Jerrold, R. Wilmette, IL 60091 (US) MRSNY, Randall, J. Los Altos Hills, CA 94022 (US) MCKAY, Derek Hamilton, Ontario L8S 3H5 (CA) (74) Representative: Kremer, Simon Mark et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)